Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species

KG Fosnacht, MD Pluth - Chemical Reviews, 2024 - ACS Publications
Hydrogen sulfide (H2S) is not only a well-established toxic gas but also an important small
molecule bioregulator in all kingdoms of life. In contemporary biology, H2S is often classified …

Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease

H Ding, Z Li, K Luo, Q Gong, X Tian - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of beta-amyloid (Aβ) protein and neurofibrillary tangles in the brain, resulting …

Small molecular fluorescent probes for Alzheimer's disease associated active species

F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …

Ultrasensitive Bio-H2S Gas Sensor Based on Cu2O-MWCNT Heterostructures

M Lu, J Chi, H Chen, Z Liu, P Shi, Z Lu, L Yin, L Du… - ACS …, 2023 - ACS Publications
Developing a respiratory analysis disease diagnosis platform for the H2S biomarker has
great significance for the real-time detection of various diseases. However, achieving highly …

H2S-based fluorescent imaging for pathophysiological processes

TT Jia, Y Zhang, JT Hou, H Niu, S Wang - Frontiers in Chemistry, 2023 - frontiersin.org
Hydrogen sulfide (H2S), as an important endogenous signaling molecule, plays a vital role
in many physiological processes. The abnormal behaviors of hydrogen sulfide in organisms …

Innovative probes with aggregation-induced emission characteristics for sensing gaseous signaling molecules

KW Lee, H Chen, Y Wan, Z Zhang, Z Huang, S Li… - Biomaterials, 2022 - Elsevier
Diseases are often accompanied by abnormal expression of gaseous signaling molecules
including nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H 2 S). Sensing …

Aggregation-Induced emission photosensitizer with lysosomal response for photodynamic therapy against cancer

Z Pan, Y Wang, N Chen, G Cao, Y Zeng, J Dong… - Bioorganic …, 2023 - Elsevier
Photosensitizers play a key role in bioimaging and photodynamic therapy (PDT) of cancer.
However, conventional photosensitizers usually do not achieve the desired efficacy in PDT …

Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine

Y Duo, L Han, Y Yang, Z Wang, L Wang… - Chemical …, 2024 - ACS Publications
Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

A novel H2O2-activated NIR fluorescent probe for imaging β-amyloid fibrils and mitochondrial viscosity

Y Guo, H Leng, Y Wang, WJ Shi, L Zhang, J Yan - Dyes and Pigments, 2022 - Elsevier
Alzheimer's disease (AD) is an incurable chronic neurodegenerative disease. Until now, β-
amyloid, mitochondrial viscosity and the relatively high concentration of hydrogen peroxide …

Structure‐Based Discovery of A Small Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) that Significantly Reduces Alzheimer's Disease Neuropathology

P Mondal, P Bai, A Gomm, G Bakiasi… - Advanced …, 2024 - Wiley Online Library
Abstract Histone deacetylase 6 (HDAC6) is one of the key histone deacetylases (HDACs)
that regulates various cellular functions including clearance of misfolded protein and …