Given their extensive role in cell signalling, GPCRs are significant drug targets; despite this,
many of these receptors have limited or no available prophylaxis. Novel drug design and …

Purified recombinant proteins are key reagents in academic and industrial research. The
ability to make these proteins quickly often relies on the availability of higher eukaryotic cell …

The field of chemical senses has made major progress in understanding the cellular
mechanisms of olfaction and taste in the past 2 decades. However, the molecular …

G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing
signals from the extracellular environment to the inside of the cell. They mediate the effects …

G protein-coupled receptors (GPCRs) are pivotal in mediating diverse physiological and
pathological processes, rendering them promising targets for drug discovery. GPCRs …

The baculovirus-insect cell system has long been deployed for a variety of applications
including for use as biopesticides, for recombinant protein production, transient transgene …

Heterologous expression of recombinant ion channel subunits in cell lines is often limited by
the presence of a low number of channels at the cell surface level. Here, we introduce a …

As a powerful eukaryotic expression vector, the baculovirus expression vector system
(BEVS) is widely applied to the production of heterogeneous proteins for research and …

Serotonin [5-hydroxytryptamine (5-HT)] acts via 13 different receptors in humans. Of these
receptor subtypes, all but 5-HT1eR have confirmed roles in native tissue and are validated …

Highlights•Arthropod GPCRs are underexploited targets for pest management.•Omics
contributes to functional characterization of GPCR-ligand pairs.•Insect GPCR structural …