Endocrine disruption by azole fungicides in fish: A review of the evidence

T Huang, Y Zhao, J He, H Cheng… - Science of The Total …, 2022 - Elsevier
Azole fungicides are widely used chemicals in agriculture and medicine. Their antifungal
activity involves inhibition of steroid biosynthesis via inhibition of several cytochrome p 450 …

[HTML][HTML] Using alternative test methods to predict endocrine disruption and reproductive adverse outcomes: do we have enough knowledge?

T Svingen, CL Schwartz, AK Rosenmai, L Ramhøj… - Environmental …, 2022 - Elsevier
Endocrine disrupting chemicals (EDCs) are a matter of great concern. They are ubiquitous in
the environment, are considered harmful to humans and wildlife, yet remain challenging to …

[HTML][HTML] Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality

A Kortenkamp, M Scholze, S Ermler, L Priskorn… - Environment …, 2022 - Elsevier
Background Semen quality in men continues to decline in Western countries, but the
contours of the issue remain obscure, in relation to contributing chemicals. Objectives To …

Adsorption behavior of azole fungicides on polystyrene and polyethylene microplastics

X Liu, DD Zhou, M Chen, YW Cao, LY Zhuang, ZH Lu… - Chemosphere, 2022 - Elsevier
Agricultural plastic films and triazole fungicides are widely used in agricultural production
process. Exposure to natural environment, agricultural plastic films will degrade into micron …

Occurrence, spatial variation, seasonal difference, and risk assessment of neonicotinoid insecticides, selected agriculture fungicides, and their transformation products …

Y Wang, Y Wan, S Li, Z He, S Xu, W Xia - Water Research, 2023 - Elsevier
Neonicotinoid insecticides (NNIs) and agricultural fungicides (including strobilurin, azole,
and morpholine fungicides) are widely used, while data on their contamination in the …

Cross-resistance to the new fungicide mefentrifluconazole in DMI-resistant fungal pathogens

H Ishii, PK Bryson, M Kayamori, T Miyamoto… - Pesticide Biochemistry …, 2021 - Elsevier
Abstract In the European Union (EU), regulation of sterol demethylation inhibiting (DMI)
fungicides is tightened due to their suspected endocrine disrupting properties. However, the …

Triazole fungicides exert neural differentiation alteration through H3K27me3 modifications: In vitro and in silico study

T Ku, X Tan, Y Liu, R Wang, L Fan, Z Ren… - Journal of Hazardous …, 2023 - Elsevier
Considering that humans are unavoidably exposed to triazole fungicides through the
esophagus, respiratory tract, and skin contact, revealing the developmental toxicity of …

Organophosphate ester flame retardants have antiandrogenic potential and affect other endocrine related endpoints in vitro and in silico

AK Rosenmai, SB Winge, M Möller, J Lundqvist… - Chemosphere, 2021 - Elsevier
Organophosphate ester flame retardants (OPFRs) are used to prevent ignition and
spreading of fire. They are present in various human matrices suggesting adult, fetal, and …

New insights into potential estrogen agonistic activity of triazole fungicides and coupled metabolic disturbance

Y Wang, X Ning, G Li, N Sang - Journal of Hazardous materials, 2022 - Elsevier
Triazole fungicides are highly effective pesticides widely used in plant protection, which has
caused potential hazards to human health and ecological safety. To fully understand their …

[HTML][HTML] Reduced ovarian cholesterol and steroid biosynthesis along with increased inflammation are associated with high DEHP metabolite levels in human ovarian …

I Varik, R Zou, A Bellavia, K Rosenberg… - Environment …, 2024 - Elsevier
Abstract The plasticizer di (2-ethylhexyl) phthalate (DEHP) is known to have endocrine-
disrupting properties mediated by its many metabolites that form upon exposure in biological …