Ultrabright renal-clearable cyanine-protein nanoprobes for high-quality NIR-II angiography and lymphography
The renal-clearable aspect of imaging agent with minimum toxicity issues and side effects is
essential for clinical translation, yet clinical near-infrared-I/II (NIR-I/II) fluorophores with timely …
essential for clinical translation, yet clinical near-infrared-I/II (NIR-I/II) fluorophores with timely …
Near‐Infrared Fluorophores Based on Heptamethine Cyanine Dyes: From Their Synthesis and Photophysical Properties to Recent Optical Sensing and Bioimaging …
NG Medeiros, CA Braga, VS Câmara… - Asian Journal of …, 2022 - Wiley Online Library
This review summarizes diverse synthetic methodologies to prepare a wide range of
heptamethine cyanine dyes, including symmetrical, unsymmetrical, and meso‐substituted …
heptamethine cyanine dyes, including symmetrical, unsymmetrical, and meso‐substituted …
[HTML][HTML] Super-stable cyanine@ albumin fluorophore for enhanced NIR-II bioimaging
Abstract Near-infrared-II (NIR-II) dyes could be encapsulated by either exogenous or
endogenous albumin to form stable complexes for deep tissue bioimaging. However, we still …
endogenous albumin to form stable complexes for deep tissue bioimaging. However, we still …
Site-specific albumin tagging with chloride-containing near-infrared cyanine dyes: molecular engineering, mechanism, and imaging applications
Q Su, Y Zhang, S Zhu - Chemical Communications, 2023 - pubs.rsc.org
Near-infrared dyes, particularly cyanine dyes, have shown great potential in biomedical
imaging due to their deep tissue penetration, high resolution, and minimal tissue …
imaging due to their deep tissue penetration, high resolution, and minimal tissue …
Role of albumin in accumulation and persistence of tumor-seeking cyanine dyes
SM Usama, GK Park, S Nomura, Y Baek… - Bioconjugate …, 2020 - ACS Publications
Some heptamethine cyanine dyes accumulate in solid tumors in vivo and persist there for
several days. The reasons why they accumulate and persist in tumors were incompletely …
several days. The reasons why they accumulate and persist in tumors were incompletely …
[HTML][HTML] Site-specific albumin tagging with NIR-II fluorogenic dye for high-performance and super-stable bioimaging
Synthetic near-infrared-II (NIR-II) dyes are promising for deep tissue imaging, yet they are
generally difficult to target a given biomolecule with high specificity. Furthermore, the …
generally difficult to target a given biomolecule with high specificity. Furthermore, the …
Multifunctional near-infrared dye IR-817 encapsulated in albumin nanoparticles for enhanced imaging and photothermal therapy in melanoma
J Wang, H Liao, J Ban, S Li, X Xiong, Q He… - International Journal …, 2023 - Taylor & Francis
Background Near-infrared cyanine dyes have high sensitivity and spatial resolution imaging
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …
capabilities, but they also have unavoidable drawbacks such as photobleaching, low water …
[HTML][HTML] Albumin-seeking dyes with adjustable assemblies in situ enable programmable imaging windows and targeting tumor imaging
Cyanine dyes are widely used organic probes for in vivo imaging due to their tunable
fluorescence. They can form complexes with endogenous albumin, resulting in enhanced …
fluorescence. They can form complexes with endogenous albumin, resulting in enhanced …
Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of …
The development of chemotherapies for glioblastoma is hindered by their limited
bioavailability and toxicity on normal brain function. To overcome these limitations, we …
bioavailability and toxicity on normal brain function. To overcome these limitations, we …
Conjugation of Palbociclib with MHI-148 has an increased cytotoxic effect for breast cancer cells and an altered mechanism of action
The CDK4/6 inhibitor palbociclib, combined with endocrine therapy, has been shown to be
effective in postmenopausal women with estrogen receptor-positive, HER2-negative …
effective in postmenopausal women with estrogen receptor-positive, HER2-negative …