The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …

Multisystem inflammatory syndrome (MIS-C) is a pediatric hyperinflammation disorder
caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It has now been …

Early increase of soluble urokinase plasminogen activator receptor (suPAR) serum levels is
indicative of increased risk of progression of coronavirus disease 2019 (COVID-19) to …

Recent studies have provided insights into the pathology of and immune response to COVID-
19,,,,,,–. However, a thorough investigation of the interplay between infected cells and the …

Background It has been reported that people with COVID‐19 and pre‐existing
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …

Calming the cytokine storm in COVID-19 | Nature Medicine Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Background Patients with severe COVID-19 develop a life-threatening hyperinflammatory
response to the virus. Interleukin (IL)-1 or IL-6 inhibitors have been used to treat this patient …

Vitamin D deficiency co-exists in patients with COVID-19. At this time, dark skin color,
increased age, the presence of pre-existing illnesses and vitamin D deficiency are features …

The pleiotropic cytokine interleukin-6 (IL-6) has been implicated in the pathogenesis of
COVID-19, but uncertainty remains about the potential benefits and harms of targeting IL-6 …

Background We and others have previously demonstrated that the endothelium is a primary
target of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and L …