One hundred years ago, Ramón y Cajal, considered by many as the founder of modern
neuroscience, stated that neurons of the adult central nervous system (CNS) are incapable …

Over the past decade, we have witnessed a flourishing of novel strategies to enhance
neuroplasticity and promote axon regeneration following spinal cord injury, and results from …

Axon regeneration can be induced across anatomically complete spinal cord injury (SCI),
but robust functional restoration has been elusive. Whether restoring neurological functions …

Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …

Three-dimensional (3D) printing and 3D bioprinting are promising technologies for a broad
range of healthcare applications from frontier regenerative medicine and tissue engineering …

Grafts of spinal-cord-derived neural progenitor cells (NPCs) enable the robust regeneration
of corticospinal axons and restore forelimb function after spinal cord injury; however, the …

A bioengineered spinal cord is fabricated via extrusion‐based multimaterial 3D bioprinting,
in which clusters of induced pluripotent stem cell (iPSC)‐derived spinal neuronal progenitor …

Neural stem/progenitor cell (NSPC) grafts can integrate into sites of spinal cord injury (SCI)
and generate neuronal relays across lesions that can provide functional benefit. To …

The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …

Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …