Beyond poly (ethylene glycol): linear polyglycerol as a multifunctional polyether for biomedical and pharmaceutical applications

A Thomas, SS Müller, H Frey - Biomacromolecules, 2014 - ACS Publications
Polyglycerols (sometimes also called “polyglycidols”) represent a class of highly
biocompatible and multihydroxy-functional polymers that may be considered as a …

Multifunctional Poly (ethylene glycol) s

B Obermeier, F Wurm, C Mangold… - Angewandte Chemie …, 2011 - Wiley Online Library
In the rapidly evolving multidisciplinary field of polymer therapeutics, tailored polymer
structures represent the key constituent to explore and harvest the potential of bioactive …

Synthesis of linear high molar mass glycidol-based polymers by monomer-activated anionic polymerization

M Gervais, AL Brocas, G Cendejas, A Deffieux… - …, 2010 - ACS Publications
Linear polyglycidols of high molar masses were prepared by the monomer-activated anionic
polymerization of the corresponding protected monomers, ethoxyethyl glycidyl ether and tert …

Poly(ethylene glycol-co-allyl glycidyl ether)s: A PEG-Based Modular Synthetic Platform for Multiple Bioconjugation

B Obermeier, H Frey - Bioconjugate Chemistry, 2011 - ACS Publications
A series of random copolymers comprising ethylene oxide (EO) and 0− 100% allyl glycidyl
ether (AGE) has been prepared by anionic ring-opening polymerization with molecular …

Double-hydrophilic linear-hyperbranched block copolymers based on poly (ethylene oxide) and poly (glycerol)

F Wurm, J Nieberle, H Frey - Macromolecules, 2008 - ACS Publications
A convenient 4-step (2-pot) approach for the synthesis of biocompatible, double hydrophilic
linear-hyperbranched block copolymers based on poly (ethylene oxide)(PEO) and poly …

Chain transfer reactions limit the molecular weight of polyglycidol prepared via alkali metal based initiating systems

M Hans, H Keul, M Moeller - Polymer, 2009 - Elsevier
Anionic polymerization of EEGE with alkali metal based initiators has been shown to yield
polyglycidol with low polydispersity indices for molecular weights up to Mn≈ 30,000. Higher …

Polyglycidols with two orthogonal protective groups: preparation, selective deprotection, and functionalization

M Erberich, H Keul, M Möller - Macromolecules, 2007 - ACS Publications
Anionic ring-opening polymerization and copolymerization of allyl glycidyl ether (AGE), tert-
butyl glycidyl ether (t BuGE), and ethoxyethyl glycidyl ether (EEGE) was performed using …

Cinnamyl-Modified Polyglycidol/Poly (ε-Caprolactone) Block Copolymer Nanocarriers for Enhanced Encapsulation and Prolonged Release of Cannabidiol

N Toncheva-Moncheva, E Dimitrov, G Grancharov… - Pharmaceutics, 2023 - mdpi.com
The present study describes the development of novel block copolymer nanocarriers of the
phytocannabinoid cannabidiol (CBD), designed to enhance the solubility of the drug in …

PEG-based multifunctional polyethers with highly reactive vinyl-ether side chains for click-type functionalization

C Mangold, C Dingels, B Obermeier, H Frey… - …, 2011 - ACS Publications
Introduction of highly reactive vinyl ether moieties along a poly (ethylene glycol)(PEG)
backbone has been realized by copolymerization of the novel epoxide monomer ethoxy …

Amino functional poly (ethylene glycol) copolymers via protected amino glycidol

B Obermeier, F Wurm, H Frey - Macromolecules, 2010 - ACS Publications
The synthesis of poly (ethylene glycol)(PEG) copolymers with multiple amino functionalities
within the chain is described, relying on an epoxide comonomer bearing a protected amino …