Stroke occurs when a cerebral blood vessel is blocked or ruptured, and it is the major cause
of death and adult disability worldwide. Various pharmacological agents have been …

Neurofibrillary tangles, which consist of highly phosphorylated tau protein, and senile
plaques (SPs) are pathological hallmarks of Alzheimer's disease (AD). In swollen axons …

Autophagy is a strictly regulated process that degrades and recycles long-lived or misfolded
proteins and damaged organelles for the maintenance of energy and function homeostasis …

Following two decades of more than 400 clinical trials centered on the “one drug, one target,
one disease” paradigm, there is still no effective disease‐modifying therapy for Alzheimer's …

Bexarotene, a retinoid X receptor (RXR) agonist, is approved by FDA to treat cutaneous T-
cell lymphoma. However, it has also demonstrated promising therapeutic potential for …

Background and Purpose—Enhancement of erythrophagocytosis by macrophages in a
timely manner can limit the toxic effects of erythrocyte metabolites and promote brain …

Adult neurogenesis defects have been demonstrated in the brains of Alzheimer's disease
(AD) patients. The neurogenesis impairment is an early critical event in the course of familiar …

Background Subarachnoid hemorrhage (SAH) is a life-threatening subtype of stroke with
high mortality and disabilities. Retinoid X receptor (RXR) has been shown to be …

Autophagy is an important biological mechanism involved in the regulation of numerous
fundamental cellular processes that are mainly associated with cellular growth and …

We manually searched professional journals with an average 5-year impact factor> 3 (from
2012 to 2016) that were known to publish manuscript with topics in stroke recovery and …