The manufacture of recombinant therapeutics is a fastest-developing section of therapeutic
pharmaceuticals and presently plays a significant role in disease management. Yeasts are …

Yeasts combine the ease of genetic manipulation and fermentation of a microorganism with
the capability to secrete and modify foreign proteins according to a general eukaryotic …

Almost all of the 200 or so approved biopharmaceuticals have been produced in one of
three host systems: the bacterium Escherichia coli, yeasts (Saccharomyces cerevisiae …

The production of recombinant therapeutic proteins is one of the fast-growing areas of
molecular medicine and currently plays an important role in treatment of several diseases …

The yeast Saccharomyces cerevisiae is a widely used cell factory for the production of fuels
and chemicals, and it is also provides a platform for the production of many heterologous …

▪ Abstract The biosynthesis of secretory and membrane proteins in the endoplasmic
reticulum (ER) yields mostly properly folded and assembled structures with full biological …

The invasive stages (zoites) of most apicomplexan parasites are polarised cells that use
their actinomyosin-powered gliding motility or “glideosome” system to move over surfaces …

Because of its eukaryotic nature, simple fermentation requirements, and pliable genetics,
there have been many attempts at improving recombinant protein production in …

Yeast Saccharomyces cerevisiae has become an attractive cell factory for production of
commodity and speciality chemicals and proteins, such as industrial enzymes and …

Exportable proteins that have significant defects in nascent polypeptide folding or subunit
assembly are frequently retained in the endoplasmic reticulum and subject to endoplasmic …