Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neuroendocrine cancer. It
most commonly presents as an indurated plaque or nodule on sun-damaged skin in elderly …

During the past 6 years, focused virus hunting has led to the discovery of nine new human
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …

This selection from the NCCN Guidelines for Merkel Cell Carcinoma (MCC) focuses on
areas impacted by recently emerging data, including sections describing MCC risk factors …

Merkel cell carcinoma (MCC) is a lethal, virus-associated cancer that lacks effective
therapies for advanced disease. Agents blocking the PD-1/PD-L1 pathway have shown …

Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Merkel cell carcinoma has been a focus of active scientific investigation in recent years and
new information on the topic has emerged. Although uncommon, this primary cutaneous …

Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …

A marked escalation in the rate of discovery of new types of human polyomavirus has
occurred over the last five years largely owing to recent technological advances in their …

Purpose: Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine
carcinoma that can be divided into two classes: virus-positive (VP) MCC, associated with …

Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are
associated with increased tumor cell invasion and metastasis. Several mechanisms have …