The formation of amyloid fibrils is a general class of protein self-assembly behaviour, which
is associated with both functional biology and the development of a number of disorders …

By averaging over atomic details, coarse-grained (CG) models provide profound
computational and conceptual advantages for studying soft materials. In particular, bottom …

Highlights•Not all IDRs undergo liquid–liquid phase separation.•IDRs are not necessary for
protein phase separation.•A stickers-and-spacers framework helps conceptualizing IDR …

Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …

Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for
biomolecular condensates underlain by liquid–liquid phase separation (LLPS) of proteins …

One of the key mechanisms used by cells to control the spatiotemporal organization of their
many components is the formation and dissolution of biomolecular condensates through …

Membraneless organelles or condensates form through liquid–liquid phase separation,,–,
which is thought to underlie gene transcription through condensation of the large-scale …

In immature oocytes, Balbiani bodies are conserved membraneless condensates implicated
in oocyte polarization, the organization of mitochondria, and long-term organelle and RNA …

Liquid-liquid phase separation (LLPS) can drive a multitude of cellular processes by
compartmentalizing biological cells via the formation of dense liquid biomolecular …

Liquid–liquid phase separation (LLPS) is an important mechanism enabling the dynamic
compartmentalization of macromolecules, including complex polymers such as proteins and …