Bone diseases such as osteoporosis and osteoarthritis have become important human
health problems, requiring a deeper understanding of the pathogenesis of related diseases …

Intervertebral disc (IVD) herniation is a leading cause of disability and lower back pain,
causing enormous socioeconomic burdens. The standard of care for disc herniation is …

The extracellular matrix (ECM) stores signaling molecules and facilitates mechanical and
biochemical signaling in cells. However, the influence of biomimetic “rejuvenation” ECM …

Background The nucleus pulposus (NP) degradation is a primary factor in intervertebral disk
degeneration (IVD) and a major contributor to low back pain. Intervertebral disk-derived …

We report the development of peptide-glycosaminoglycan hydrogels as injectable
biomaterials for load-bearing soft tissue repair. The hydrogels are injectable as a liquid for …