Physical activity and cancer outcomes: a precision medicine approach

CM Friedenreich, HK Neilson, MS Farris… - Clinical Cancer …, 2016 - AACR
There is increasing interest in applying a precision medicine approach to understanding
exercise as a potential treatment for cancer. We aimed to inform this new approach by …

Cancer therapy–induced cardiotoxicity: basic mechanisms and potential cardioprotective therapies

VS Hahn, DJ Lenihan, B Ky - Journal of the American Heart …, 2014 - Am Heart Assoc
The patient is a 63-year-old man with a history of wellcontrolled hypertension who is
diagnosed with diffuse large B-cell lymphoma and treated with a doxorubicincontaining …

[HTML][HTML] Physical activity and survival after prostate cancer

CM Friedenreich, Q Wang, HK Neilson, KA Kopciuk… - European urology, 2016 - Elsevier
Background Despite the high global prevalence of prostate cancer (PCa), few epidemiologic
studies have assessed physical activity in relation to PCa survival. Objective To evaluate …

Exercise and risk of cardiovascular events in women with nonmetastatic breast cancer

LW Jones, LA Habel, E Weltzien, A Castillo… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Cardiovascular disease (CVD) is a leading cause of death among women with
nonmetastatic breast cancer. Whether exercise is associated with reductions in CVD risk in …

Skeletal muscle mitochondria: a major player in exercise, health and disease

AP Russell, VC Foletta, RJ Snow, GD Wadley - Biochimica et biophysica …, 2014 - Elsevier
Background Maintaining skeletal muscle mitochondrial content and function is important for
sustained health throughout the lifespan. Exercise stimulates important key stress signals …

[HTML][HTML] Antineoplastic drug-induced cardiotoxicity: a redox perspective

G Varricchi, P Ameri, C Cadeddu, A Ghigo… - Frontiers in …, 2018 - frontiersin.org
Antineoplastic drugs can be associated with several side effects, including cardiovascular
toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX …

Association of exercise with mortality in adult survivors of childhood cancer

JM Scott, N Li, Q Liu, Y Yasui, W Leisenring… - JAMA …, 2018 - jamanetwork.com
Importance Adult survivors of childhood cancer are at excess risk for mortality compared with
the general population. Whether exercise attenuates this risk is not known. Objective To …

Exercise and risk of major cardiovascular events in adult survivors of childhood hodgkin lymphoma: a report from the childhood cancer survivor study

LW Jones, Q Liu, GT Armstrong, KK Ness… - Journal of Clinical …, 2014 - ascopubs.org
Purpose Survivors of Hodgkin lymphoma (HL) are at increased risk of treatment-related
cardiovascular (CV) events; whether exercise modifies this risk is unknown. Methods …

From molecular mechanisms to clinical management of antineoplastic drug-induced cardiovascular toxicity: a translational overview

CG Tocchetti, C Cadeddu, D Di Lisi… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Antineoplastic therapies have significantly improved the prognosis of oncology
patients. However, these treatments can bring to a higher incidence of side-effects, including …

Effects of high‐intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial

SC Adams, DS DeLorey, MH Davenport… - Cancer, 2017 - Wiley Online Library
BACKGROUND Testicular cancer survivors (TCS) have an increased risk of treatment‐
related cardiovascular disease (CVD), which may limit their overall survival. We evaluated …