The discovery of isozyme-selective histone deacetylase (HDAC) inhibitors is critical for
understanding the biological functions of individual HDACs and for validating HDACs as …

Disclosed are selective histone deactylase inhibitors (HDACi) that having Formula I.
Specifically, the disclosed subject matter relates to compounds having activity as selective …

Histone deacetylases inhibitors (HDACIs) and compositions containing the same are
disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC pro …

Disclosed are methods whereby an effective amount of a HDAC6 inhibitor is used to activate
a subjects T-cell response to tumor or tumor vaccine. Methods of using HDAC6 inhibitors to …

US10918638B2 - Histone deacetylase 6 inhibition for enhancing T-cell function during anti-tumor
response and tumor-peptide vaccination - Google Patents US10918638B2 - Histone …

Aldana-Masangkay, et al.,“The Role of HDAC6 in Cancer”, J Biomed Biotechnol vol. 2011,
article 875824, 2010, 1-10. Barnden, et al.,“Defective TCR expression in transgenic mice …