Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases

MA Incalza, R D'Oria, A Natalicchio, S Perrini… - Vascular …, 2018 - Elsevier
Reactive oxygen species (ROS) are reactive intermediates of molecular oxygen that act as
important second messengers within the cells; however, an imbalance between generation …

[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

[HTML][HTML] VCAM-1 as a predictor biomarker in cardiovascular disease

MF Troncoso, J Ortiz-Quintero… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The vascular cellular adhesion molecule-1 (VCAM-1) is a protein that canonically
participates in the adhesion and transmigration of leukocytes to the interstitium during …

Metabolic and vascular effect of the Mediterranean diet

A Tuttolomondo, I Simonetta, M Daidone… - International journal of …, 2019 - mdpi.com
Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

[HTML][HTML] Atherosclerosis: process, indicators, risk factors and new hopes

M Rafieian-Kopaei, M Setorki, M Doudi… - … journal of preventive …, 2014 - ncbi.nlm.nih.gov
Background: Atherosclerosis is the major cause of morbidities and mortalities worldwide. In
this study we aimed to review the mechanism of atherosclerosis and its risk factors, focusing …

Monocyte recruitment during infection and inflammation

C Shi, EG Pamer - Nature reviews immunology, 2011 - nature.com
Monocytes originate from progenitors in the bone marrow and traffic via the bloodstream to
peripheral tissues. During both homeostasis and inflammation, circulating monocytes leave …

Antioxidants and atherosclerosis: mechanistic aspects

K Malekmohammad, RDE Sewell, M Rafieian-Kopaei - Biomolecules, 2019 - mdpi.com
Atherosclerosis is a chronic inflammatory disease which is a major cause of coronary heart
disease and stroke in humans. It is characterized by intimal plaques and cholesterol …

Adherence to the mediterranean diet and inflammatory markers

A Sureda, MM Bibiloni, A Julibert, C Bouzas, E Argelich… - Nutrients, 2018 - mdpi.com
The aim was to assess inflammatory markers among adults and adolescents in relation to
the adherence to the Mediterranean diet. A random sample (219 males and 379 females) of …

The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis

A Kowalczyk, P Kleniewska, M Kolodziejczyk… - Archivum immunologiae …, 2015 - Springer
Abstract Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by
endothelial cells. It acts through two types of receptors: ETA and ETB. Apart from a …

Endothelial dysfunction and its clinical implications

P Poredos, AV Poredos, I Gregoric - Angiology, 2021 - journals.sagepub.com
Endothelial dysfunction (ED) plays a substantial role in the pathogenesis of atherosclerosis
and some other vascular diseases. ED has been demonstrated in patients with …