Urine as a source of liquid biopsy for cancer

M Oshi, V Murthy, H Takahashi, M Huyser, M Okano… - Cancers, 2021 - mdpi.com
Simple Summary Tissue biopsy is essential for diagnosis and characterization of a tumor.
Recently circulating tumor cells and other tumor-derived nucleic acid can be detected from …

Extracellular vesicles in urological malignancies: an update

J Linxweiler, K Junker - Nature reviews Urology, 2020 - nature.com
Extracellular vesicles (EVs) have an essential functional role in local tumour progression,
metastatic spread and the emergence of drug resistance in bladder, kidney and prostate …

Insights into exosomal non-coding RNAs sorting mechanism and clinical application

Y Qiu, P Li, Z Zhang, M Wu - Frontiers in Oncology, 2021 - frontiersin.org
Exosomes are natural nanoscale bilayer phospholipid vesicles that can be secreted by
almost all types of cells and are detected in almost all types of body fluids. Exosomes are …

A comprehensive overview of liquid biopsy applications in pediatric solid tumors

FW Janssen, NSM Lak, CY Janda, LA Kester… - NPJ precision …, 2024 - nature.com
Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with
potential applications during all stages of patient care, from diagnosis to long-term follow-up …

[HTML][HTML] Long non-coding RNAs in oncourology

I Gareev, Y Gileva, A Dzidzaria, O Beylerli… - Non-coding RNA …, 2021 - Elsevier
For several decades, research in tumor biology has focused on the involvement of genes
encoding a protein. Only recently has it been discovered that a whole class of molecules …

Small non-coding RNA profiling in plasma extracellular vesicles of bladder cancer patients by next-generation sequencing: expression levels of miR-126-3p and piR …

AA Sabo, G Birolo, A Naccarati, MP Dragomir, S Aneli… - Cancers, 2020 - mdpi.com
Bladder cancer (BC) is the tenth most frequent cancer worldwide. Due to the need for
recurrent cystoscopies and the lack of non-invasive biomarkers, BC is associated with a high …

Diagnostic liquid biopsy biomarkers in renal cell cancer

RC Zieren, PJ Zondervan, KJ Pienta, A Bex… - Nature Reviews …, 2024 - nature.com
The clinical presentation of renal cell cancer (RCC) is shifting towards incidental and early
detection, creating new challenges in RCC diagnosis. Overtreatment might be reduced with …

[HTML][HTML] Liquid biopsy in urothelial carcinoma: Detection techniques and clinical applications

S Wu, R Li, Y Jiang, J Yu, J Zheng, Z Li, M Li… - Biomedicine & …, 2023 - Elsevier
The types of urothelial carcinoma (UC) include urothelial bladder cancer and upper tract
urothelial carcinoma. Current diagnostic techniques cannot meet the needs of patients …

[HTML][HTML] Ratiometric fluorescent detection of exosomal piRNA-823 based on Au NCs/UiO-66-NH2 and target-triggered rolling circle amplification

Y Tong, B Guan, Z Sun, X Dong, Y Chen, Y Li, Y Jiang… - Talanta, 2023 - Elsevier
Abstract piR-823 is a newly discovered colorectal cancer marker with high diagnostic
efficacy. However, the current quantification methods have complicated operations and high …

[HTML][HTML] Exploring the Role of Noncoding RNAs in Cancer Diagnosis, Prognosis, and Precision Medicine.

B Eldakhakhny, AM Sutaih, MA Siddiqui… - Non-coding RNA …, 2024 - Elsevier
This review article studies the complex field of noncoding RNAs (ncRNAs) in cancer biology,
focusing on their potential use as biomarkers and therapeutic targets. ncRNAs include …