Both environmental and genetic triggers factor into the etiology of autoimmune thyroid
disease (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT). Although …

Lysophospholipids encompass a diverse range of small, membrane‐derived phospholipids
that act as extracellular signals. The signalling properties are mediated by 7 …

Autoimmune thyroid disease is the most common autoimmune disease and is highly
heritable. Here, by using a genome-wide association study of 30,234 cases and 725,172 …

Ideal biomarkers used for disease diagnosis should display deviating levels in affected
individuals only and be robust to factors unrelated to the disease. Here we show the impact …

To fine map association signals of human leukocyte antigen (HLA) variants in the major
histocompatibility complex (MHC) region, we constructed a Japanese population-specific …

Vitiligo is an autoimmune disease with a strong genetic component, characterized by areas
of depigmented skin resulting from loss of epidermal melanocytes. Genetic factors are …

Thyroid diseases, including autoimmune thyroid diseases and thyroid cancer, are known to
have high heritability. Family and twin studies have indicated that genetics plays a major …

Abstract In Graves' disease (GD), a combination of genetic, epigenetic and environmental
factors causes an autoimmune response to the thyroid gland, characterized by lymphocytic …

Implementing precision medicine for complex diseases such as chronic obstructive lung
disease (COPD) will require extensive use of biomarkers and an in-depth understanding of …

Autoimmune thyroid diseases (AITD) are a group of both B cell-and T cell-mediated organ-
specific autoimmune diseases. Graves' disease and Hashimoto thyroiditis are the two main …