Cerebellar circuitry as a neuronal machine

M Ito - Progress in neurobiology, 2006 - Elsevier
Shortly after John Eccles completed his studies of synaptic inhibition in the spinal cord, for
which he was awarded the 1963 Nobel Prize in physiology/medicine, he opened another …

Cerebellar long-term depression: characterization, signal transduction, and functional roles

M Ito - Physiological reviews, 2001 - journals.physiology.org
Cerebellar Purkinje cells exhibit a unique type of synaptic plasticity, namely, long-term
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …

Optogenetic countering of glial acidosis suppresses glial glutamate release and ischemic brain damage

K Beppu, T Sasaki, KF Tanaka, A Yamanaka… - Neuron, 2014 - cell.com
The brain demands high-energy supply and obstruction of blood flow causes rapid
deterioration of the healthiness of brain cells. Two major events occur upon ischemia …

Application of an optogenetic byway for perturbing neuronal activity via glial photostimulation

T Sasaki, K Beppu, KF Tanaka… - Proceedings of the …, 2012 - National Acad Sciences
Dynamic activity of glia has repeatedly been demonstrated, but if such activity is
independent from neuronal activity, glia would not have any role in the information …

Memory trace of motor learning shifts transsynaptically from cerebellar cortex to nuclei for consolidation

F Shutoh, M Ohki, H Kitazawa, S Itohara, S Nagao - Neuroscience, 2006 - Elsevier
Adaptation of ocular reflexes is a prototype of motor learning. While the cerebellum is
acknowledged as the critical site for motor learning, the functional differences between the …

A comparison of video and magnetic search coil recordings of mouse eye movements

JS Stahl, AM Van Alphen, CI De Zeeuw - Journal of neuroscience methods, 2000 - Elsevier
Interest in connecting molecular biology and behavior is motivating research into the eye
movements of mice. Unfortunately, recording eye movements in this diminutive animal is …

Identification of retinal ganglion cells and their projections involved in central transmission of information about upward and downward image motion

K Yonehara, H Ishikane, H Sakuta, T Shintani… - PloS one, 2009 - journals.plos.org
The direction of image motion is coded by direction-selective (DS) ganglion cells in the
retina. Particularly, the ON DS ganglion cells project their axons specifically to terminal …

Long-term depression as a model of cerebellar plasticity

M Ito, K Yamaguchi, S Nagao, T Yamazaki - Progress in brain research, 2014 - Elsevier
Long-term depression (LTD) here concerned is persistent attenuation of transmission
efficiency from a bundle of parallel fibers to a Purkinje cell. Uniquely, LTD is induced by …

Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release

T Sadakata, W Kakegawa, A Mizoguchi… - Journal of …, 2007 - Soc Neuroscience
Ca2+-dependent activator protein for secretion 2 (CAPS2/CADPS2) is a secretory granule-
associated protein that is abundant at the parallel fiber terminals of granule cells in the …

The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation

H Cahill, J Nathans - PloS one, 2008 - journals.plos.org
The optokinetic reflex (OKR), which serves to stabilize a moving image on the retina, is a
behavioral response that has many favorable attributes as a test of CNS function. The OKR …