Abstract The Surveillance, Epidemiology, and End Results (SEER) program of the National
Cancer Institute collects data on cancer diagnoses, treatment, and survival for approximately …

Genome instability is a hallmark of cancer cells and can be accelerated by defects in cellular
responses to DNA damage. This feature of malignant cells opens new avenues for tumor …

Background It has been suggested that colorectal cancer be regarded as several subgroups
defined according to tumor location rather than as a single entity. The current study aimed to …

DNA damage response, a key factor involved in maintaining genome integrity and stability,
consists of several kinase-dependent signaling pathways, which sense and transduce DNA …

Background Mucinous differentiation occurs in 5–15 per cent of colorectal
adenocarcinomas. This subtype of colorectal cancer responds poorly to chemoradiotherapy …

Human epidermal growth factor receptor 2 (HER2/ERBB2) factor is known to be implicated
in many malignancies and the potential of it as a prognostic biomarker was reported years …

Colorectal cancer (CRC) biomarker database (CBD) was established based on 870
identified CRC biomarkers and their relevant information from 1115 original articles in …

Mucinous adenocarcinoma (MAC) is defined by the presence of extracellular mucin
covering more than 50% of the tumour area; however, MAC is histologically heterogeneous …

Abstract Toll-like receptor (TLR) 2 is a key regulator of innate immune responses and has
been shown to play an important role in inflammation-associated cancers. In this study, we …

Background Mucinous adenocarcinoma (MC) is a rare histological subtype of colorectal
adenocarcinoma. Previous studies investigating the prognosis of MC have conflicting results …