One in three people will be diagnosed with cancer during their lifetime. The community of
cancer patients is growing, and several common cancers are becoming increasingly …

There are various cancer treatments at present, and chemotherapy is one of the main
methods. Chemotherapy‐related cognitive impairment (CRCI), as one of the side effects of …

Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are
associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used …

Although doxorubicin (Dox) is an effective chemotherapy medication used extensively in the
treatment of breast cancer, it frequently causes debilitating neurological deficits known as …

Cisplatin is used to combat solid tumors. However, patients treated with cisplatin often
develop cognitive impairments, sensorimotor deficits, and peripheral neuropathy. There is …

Nanotechnology has emerged as a promising approach for the targeted delivery of
therapeutic agents while improving their efficacy and safety. As a result, nanomaterial …

Breast cancer is the most common female malignancy in both the developed and
developing world. Doxorubicin is one of the most commonly used chemotherapies for breast …

Abstract Toll-like receptor 4 (TLR4) is a crucial receptor in neuroinflammation and apoptotic
neuronal death, and increasing evidences indicated that β2-microglobulin (B2M) is thought …

Doxorubicin (Dox), a powerful chemotherapeutic agent, has been shown to cause
cardiotoxicity and neurotoxicity. Ranolazine, a drug that is commonly used to treat patients …

Neurotoxic side effects of chemotherapy include deficits in attention, memory, and executive
functioning. Currently, there are no FDA-approved therapies. In mice, cisplatin causes long …