Aims Biofilm-related infection is a major complication that occurs in orthopaedic surgery.
Various treatments are available but efficacy to eradicate infections varies significantly. A …

Bioluminescence imaging (BLI) is a powerful method for visualizing biological processes
and tracking cells. Engineered bioluminescent bacteria that utilize luciferase-catalyzed …

Tools for noninvasive detection of bacterial pathogens are needed but are not currently
available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) …

The idea that most bacteria in nature are attached to surfaces was recognized as early as
1933 when Henrici stated after investigating fresh-water bacteria that “it is quite evident that …

In the field of orthopedics, an infected bone defect is a refractory disease accompanied by
bone infection and defects as well as aggravated circulation. There are currently no …

Introduction Topical agents typically remain in the wound site for time duration that are too
short to effectively eradicate MRSA tradition formation of BZK that can be maintained within …

Polymethyl methacrylate (PMMA) bone cement is commonly used in orthopedic surgeries to
fill the bone defects or fix the prostheses. These cements are usually containing amounts of …

In diagnosing chronic orthopedic implant infections culture of sonicate represents a
supplement to tissue cultures. However, the extent to which biofilm forms on implant …

Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process
involving the bone marrow, bone cortex, periosteum, and surrounding soft tissue, which can …

Abstract Evaluation of patients that may be infected is challenging. Imaging to identify or
localize a site of infection is often limited because of the nonspecific nature of the findings on …