Parkinson's disease (PD) and Alzheimer's disease (AD), the most common
neurodegenerative diseases, are caused by both genetic and environmental factors …

Manganese (Mn) is an abundant, naturally occurring element in the Earth's crust. It is most
frequently found in the form of oxides, carbonates, and silicates. 1 It is also one out of seven …

Sleep is dependent upon prior brain activities, eg, after prolonged wakefulness sleep
rebound occurs. These effects are mediated, in part, by humoral sleep regulatory …

Dopaminergic neurons that constitute the nigrostriatal pathway are characterized by singular
electrical properties that allow them to discharge in vivo spontaneously in a spectrum of …

This study aimed to screen the target miRNAs and to investigate the differential miR‐
3557/324‐targeted signal mechanisms in the rats' model of Parkinson's disease (PD) with …

BACKGROUND: Recent studies showed changes in cerebral protein expression up to 3
days after desflurane anesthesia in rats. In the present study, we investigated the existence …

Ubiquitin (Ub) carboxy terminal hydrolase (UCH)-L1 and UCH-L3 are two of the
deubiquitinating enzymes expressed in the brain. Both gad mice, which lack UCH-L1 …

Purinergic signaling is involved in multiple pain processes. P2X3 receptor is a key target in
pain therapeutics, while A1 adenosine receptor signaling plays a role in analgesia …

Loss‐of‐function mutations of the parkin gene causes an autosomal recessive juvenile‐
onset form of Parkinson's disease (AR‐JP). Parkin was shown to function as a RING‐type E3 …

Zinc deficiency has been associated with impaired learning and memory function in animals
and human beings. However, the molecular mechanisms remain obscure. In light of …