Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Block copolymer solution self‐assembly: Recent advances, emerging trends, and applications

M Karayianni, S Pispas - Journal of Polymer Science, 2021 - Wiley Online Library
The self‐assembly process of block copolymers (BCPs) in solution has been at the focus of
extended scientific research over the past several decades owing to the astonishing …

Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids

AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

A bioactive dextran-based hydrogel promote the healing of infected wounds via antibacterial and immunomodulatory

L Zhou, L Zhou, C Wei, R Guo - Carbohydrate Polymers, 2022 - Elsevier
Bacterial infection will attack the wound and aggravate inflammation, which is the main
reason for the difficulty in wound healing. Here, we reported a dextran-based hydrogel …

An M2 macrophage-polarized anti-inflammatory hydrogel combined with mild heat stimulation for regulating chronic inflammation and impaired angiogenesis of …

Y Yuan, D Fan, S Shen, X Ma - Chemical Engineering Journal, 2022 - Elsevier
Abstract At present, approximately 19–34% of diabetic patients (nearly 450 million) may
have complications involving diabetic foot ulcers (DFUs). Wound healing of DFUs still faces …

Progress in polymer single-chain based hybrid nanoparticles

Y Shao, Z Yang - Progress in Polymer Science, 2022 - Elsevier
Precise control of molecular hierarchical organization has endowed biological systems with
unique functions, which inspires great efforts in the synthesis of artificial mimics. Polymeric …

Injectable thermosensitive hydrogel systems based on functional PEG/PCL block polymer for local drug delivery

H Deng, A Dong, J Song, X Chen - Journal of Controlled Release, 2019 - Elsevier
Injectable in situ thermosensitive hydrogels have potential applications in tissue engineering
and drug delivery. The hydrogel formulations exist as aqueous solutions at room …

α-Amino acid N-carboxyanhydride (NCA)-derived synthetic polypeptides for nucleic acids delivery

Y Liu, L Yin - Advanced Drug Delivery Reviews, 2021 - Elsevier
In recent years, gene therapy has come into the spotlight for the prevention and treatment of
a wide range of diseases. Polypeptides have been widely used in mediating nucleic acid …

Recent Advances and Future Perspectives of Synthetic Polypeptides from N-Carboxyanhydrides

Z Song, Z Tan, J Cheng - Macromolecules, 2019 - ACS Publications
Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that
have found broad biomedical applications. Ring-opening polymerization of N …

Macromolecular design and preparation of polymersomes

J Lefley, C Waldron, CR Becer - Polymer Chemistry, 2020 - pubs.rsc.org
From drug delivery to nanoreactors and protocells, polymersomes have gained
considerable interest from researchers due to their novel applications. However, one of the …