At least 150 human proteins are glycosylphosphatidylinositol-anchored proteins (GPI-APs).
The protein moiety of GPI-APs lacking transmembrane domains is anchored to the plasma …

The wall gives a Saccharomyces cerevisiae cell its osmotic integrity; defines cell shape
during budding growth, mating, sporulation, and pseudohypha formation; and presents …

Glycosylphosphatidylinositols (GPIs) act as membrane anchors of many eukaryotic cell
surface proteins. GPIs in various organisms have a common backbone consisting of …

Hyperphosphatasia mental retardation (HPMR) syndrome is an autosomal recessive form of
mental retardation with distinct facial features and elevated serum alkaline phosphatase. We …

Glycosylphosphatidylinositol (GPI) anchoring of cell surface proteins is the most complex
and metabolically expensive of the lipid posttranslational modifications described to date …

Like most other eukaryotes, Saccharomyces cerevisiae harbors a GPI anchoring machinery
and uses it to attach proteins to membranes. While a few GPI proteins reside permanently at …

At least 150 different human proteins are anchored to the outer leaflet of the plasma
membrane via glycosylphosphatidylinositol (GPI). GPI preassembled in the endoplasmic …

The post-translational glycosylation of select proteins by O-linked mannose (O-mannose or
O-man) is a conserved modification from yeast to humans and has been shown to be …

Several human pathogens are to be found within the bacterial genus Mycobacterium,
notably Mycobacterium tuberculosis, the causative agent of tuberculosis, one of the most …

Hyperphosphatasia with mental retardation syndrome (HPMRS), an autosomal-recessive
form of intellectual disability characterized by facial dysmorphism, seizures …