Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both
genetic and non‐genetic factors. The precise modus operandi for vitiligo pathogenesis has …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are formed under
physiological conditions in the human body and are removed by cellular antioxidant defense …

In this study, an in vitro model of the blood-brain barrier, consisting of porcine brain-derived
microvascular endothelial cells (BMEC), was used to evaluate the mechanism of hypoxia …

The discovery of nitric oxide (NO) as an intercellular messenger or neurotransmitter opened
a new era for identifying the important mechanisms underlying physiological and …

To date there is ample evidence that patients with vitiligo accumulate millimolar
concentrations of hydrogen peroxide (H 2 O 2) in their epidermis as well as in their blood …

Copper (Cu) is an essential nutrient whose requirement is increased during pregnancy and
lactation. These represent times of critical growth and development, and the fetus and …

Two natural products Polypodium leucotomos extract (PL) and kojic acid (KA) were tested
for their ability to scavenge reactive oxygen species (· OH,· O2-, H2O2, ¹O2) in phosphate …

Vitiligo is a depigmenting disorder resulting from the loss of melanocytes in the skin and
affects 1-4% of the world population. Incidence of vitiligo is found to be 0.5-2.5% in India with …

The hypothesis that decreases in brain blood flow during respiration of hyperbaric oxygen
result from inactivation of nitric oxide (NO) by superoxide anions (O 2–) is proposed …

Oxidative stress has been implicated as the initial triggering event in vitiligo pathogenesis
leading to melanocyte destruction. Here, we report a significant increase in oxidative stress …