What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks
In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
efforts towards the development of antiviral metallodrugs. Classical compounds such as …
Buthionine sulfoximine and chemoresistance in cancer treatments: a systematic review with meta-analysis of preclinical studies
C dos Reis Oliveira, JC Pereira… - Journal of Toxicology …, 2023 - Taylor & Francis
Buthionine sulfoximine (BSO) is a synthetic amino acid that blocks the biosynthesis of
reduced glutathione (GSH), an endogenous antioxidant cellular component present in tumor …
reduced glutathione (GSH), an endogenous antioxidant cellular component present in tumor …
Synthesis and characterization of new complexes of nickel (II), palladium (II) and platinum (II) with derived sulfonamide ligand: structure, DFT study, antibacterial and …
The synthesis, characterization and biological study of new nickel (II), palladium (II), and
platinum (II) complexes with sulfamethoxazole ligand used in pharmaceutical field, were …
platinum (II) complexes with sulfamethoxazole ligand used in pharmaceutical field, were …
Adsorption of l-buthionine sulfoximine on Bi (III) and Eu (III) co-substituted hydroxyapatite nanocrystals for enhancing radiosensitization effects
GM Quindoza III, Y Nakagawa, Y Anraku… - Colloids and Surfaces B …, 2023 - Elsevier
Cancer theranostics combines therapeutic and diagnostic capabilities into a single system to
treat cancer efficiently. Biocompatible nanomaterials can be engineered to exhibit cancer …
treat cancer efficiently. Biocompatible nanomaterials can be engineered to exhibit cancer …
Antibacterial activities and antiproliferative assays over a tumor cells panel of a silver complex with 4-aminobenzoic acid: Studies in vitro of sustained release using …
NAS Aquaroni, DH Nakahata, SC Lazarini… - Journal of inorganic …, 2020 - Elsevier
The aims of this work were to evaluate the antibacterial and antiproliferative potential in vitro
of the metal complex with 4-aminobenzoic acid (Ag-pABA) and a drug delivery system …
of the metal complex with 4-aminobenzoic acid (Ag-pABA) and a drug delivery system …
A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
Currently, the evolving and complex mechanisms of bacterial resistance to conventional
antibiotics are increasing, while alternative medicines are drying up, which urges the need …
antibiotics are increasing, while alternative medicines are drying up, which urges the need …
[HTML][HTML] CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and …
Snake venoms are rich and intriguing sources of biologically-active molecules that act on
target cells, modulating a diversity of physiological functions and presenting promising …
target cells, modulating a diversity of physiological functions and presenting promising …
Synthesis, spectroscopic characterization and in vitro antibacterial and antiviral activities of novel silver (I) complexes with mafenide and ethyl-mafenide
PG Esquezaro, CM Manzano, DH Nakahata… - Journal of Molecular …, 2021 - Elsevier
Two novel silver (I) complexes with the antibacterial sulfa drugs mafenide (Maf) and ethyl-
mafenide (eMaf) are presented in this article. Elemental analysis indicated the 1: 1 metal …
mafenide (eMaf) are presented in this article. Elemental analysis indicated the 1: 1 metal …
Synthesis, crystal structure investigation, DFT analyses and antimicrobial studies of silver (I) complexes with N, N, N′, N′′-tetrakis (2-hydroxyethyl/propyl) …
The synthesis, crystal structures, DFT and antimicrobial studies of three novel complexes of
silver:[Ag (THEEN)] 2 (PIC) 2 (1),[Ag (THPEN)] 2 (PIC) 2 (2) and [Ag (TEAH3) 2](PIC)(3) …
silver:[Ag (THEEN)] 2 (PIC) 2 (1),[Ag (THPEN)] 2 (PIC) 2 (2) and [Ag (TEAH3) 2](PIC)(3) …
Impact of the functionalized tetrazole ring on the electrochemical behavior and biological activities of novel nickel (II) complexes with a series of tetrazole derivatives
Six new nickel (II) complexes with a series of tetrazole derivatives functionalized by different
substituents {5-(2-(1-Benzyltetrazol-5-yl) phenyl)-2-ethyl-4-methylthiazole (L 1), 1-Benzyl-5 …
substituents {5-(2-(1-Benzyltetrazol-5-yl) phenyl)-2-ethyl-4-methylthiazole (L 1), 1-Benzyl-5 …