Haemostasis in chronic kidney disease

J Lutz, J Menke, D Sollinger, H Schinzel… - Nephrology Dialysis …, 2014 - academic.oup.com
The coagulation system has gained much interest again as new anticoagulatory substances
have been introduced into clinical practice. Especially patients with renal failure are likely …

Chronic kidney disease: national clinical guideline for early identification and management in adults in primary and secondary care

National Collaborating Centre for Chronic Conditions … - 2008 - books.google.com
Page 1 The National Collaborating Centre for Chronic Conditions CHRONIC KIDNEY
DISEASE National clinical guideline for early identification and management in adults in …

Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis

EVOLVE Trial Investigators - New England Journal of Medicine, 2012 - Mass Medical Soc
Background Disorders of mineral metabolism, including secondary hyperparathyroidism, are
thought to contribute to extraskeletal (including vascular) calcification among patients with …

Platelet dysfunction in renal failure

P Boccardo, G Remuzzi… - Seminars in thrombosis …, 2004 - thieme-connect.com
Patients with end-stage renal disease suffer from complex hemostatic disorders. Uremic
patients show a bleeding diathesis that is mainly due to abnormalities of primary …

Hematology: issues in the dialysis patient: platelet dysfunction and end‐stage renal disease

D Kaw, D Malhotra - Seminars in dialysis, 2006 - Wiley Online Library
Patients with end‐stage renal disease (ESRD) develop hemostatic disorders mainly in the
form of bleeding diatheses. Hemorrhage can occur at cutaneous, mucosal, or serosal sites …

P-selectin-and CD63-exposing platelet microparticles reflect platelet activation in peripheral arterial disease and myocardial infarction

PM van der Zee, E Biro, Y Ko, RJ de Winter… - Clinical …, 2006 - academic.oup.com
Abstract Background: Platelet-derived microparticles (PMPs) are generally considered a
marker of platelet activation in cardiovascular disease. We studied the extent to which PMP …

Pharmacology of the New P2Y12 Receptor Inhibitors: Insights on Pharmacokinetic and Pharmacodynamic Properties

N Ferri, A Corsini, S Bellosta - Drugs, 2013 - Springer
The P2Y 12 receptor is a key player in platelet activation and represents an effective
pharmacological target for the inhibition of platelet aggregation and prevention of …

[HTML][HTML] Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia

D Mezzano, EO Pais, E Aranda, O Panes, P Downey… - Kidney international, 2001 - Elsevier
Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and
endothelial dysfunction in uremia. Background Several cardiovascular risk factors are …

Decreased glomerular filtration rate is a risk factor for hemorrhagic but not for ischemic stroke: the Rotterdam Study

MJ Bos, PJ Koudstaal, A Hofman, MMB Breteler - Stroke, 2007 - Am Heart Assoc
Background and Purpose—Persons with early stages of chronic kidney disease, defined by
a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular …

The emerging role of coagulation proteases in kidney disease

T Madhusudhan, BA Kerlin, B Isermann - Nature reviews nephrology, 2016 - nature.com
A role of coagulation proteases in kidney disease beyond their function in normal
haemostasis and thrombosis has long been suspected, and studies performed in the past 15 …