[HTML][HTML] Early detection of pancreatic cancer: opportunities and challenges
Most patients with pancreatic ductal adenocarcinoma (PDAC) present with symptomatic,
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
surgically unresectable disease. Although the goal of early detection of PDAC is laudable …
ACG clinical guideline: diagnosis and management of pancreatic cysts
GH Elta, BK Enestvedt, BG Sauer… - Official journal of the …, 2018 - journals.lww.com
Pancreatic cysts are very common with the majority incidentally identified. There are several
types of pancreatic cysts; some types can contain cancer or have malignant potential …
types of pancreatic cysts; some types can contain cancer or have malignant potential …
From somatic mutation to early detection: insights from molecular characterization of pancreatic cancer precursor lesions
CG Fischer, LD Wood - The Journal of pathology, 2018 - Wiley Online Library
Pancreatic cancer arises from noninvasive precursor lesions, including pancreatic
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …
intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and …
Predictive ability of pancreatic cyst fluid biomarkers: a systematic review and meta-analysis
Background Mucinous pancreatic cysts harbor the potential to progress to highly lethal
pancreatic ductal adenocarcinoma (PDAC). Since these precursor cysts require cancer …
pancreatic ductal adenocarcinoma (PDAC). Since these precursor cysts require cancer …
Genetics of familial and sporadic pancreatic cancer
LD Wood, MB Yurgelun, MG Goggins - Gastroenterology, 2019 - Elsevier
In the previous decade, comprehensive genomic analyses have yielded important insights
about the genetic alterations that underlie pancreatic tumorigenesis. Whole-exome and …
about the genetic alterations that underlie pancreatic tumorigenesis. Whole-exome and …
Pancreatic juice mutation concentrations can help predict the grade of dysplasia in patients undergoing pancreatic surveillance
Purpose: The measurement of mutations in pancreatic juice samples collected from the
duodenum during endoscopic ultrasound (EUS) may improve the diagnostic evaluation of …
duodenum during endoscopic ultrasound (EUS) may improve the diagnostic evaluation of …
Predicting the grade of dysplasia of pancreatic cystic neoplasms using cyst fluid DNA methylation markers
Purpose: Pancreatic cysts are common and pose diagnostic and management challenges.
Pancreatic cyst fluid markers have the potential to aid in the management of cysts with …
Pancreatic cyst fluid markers have the potential to aid in the management of cysts with …
Humoral predictors of malignancy in IPMN: a review of the literature
EC Nista, T Schepis, M Candelli, L Giuli… - International Journal of …, 2021 - mdpi.com
Pancreatic cystic lesions are increasingly detected in cross-sectional imaging. Intraductal
papillary mucinous neoplasm (IPMN) is a mucin-producing subtype of the pancreatic cyst …
papillary mucinous neoplasm (IPMN) is a mucin-producing subtype of the pancreatic cyst …
Validation of biomarkers for early detection of pancreatic cancer: summary of the alliance of pancreatic cancer consortia for biomarkers for early detection workshop
Pancreatic cancer is the third leading cause of cancer death in the United States, and the 5-
year relative survival for patients diagnosed with pancreatic cancer is less than 10%. Early …
year relative survival for patients diagnosed with pancreatic cancer is less than 10%. Early …
Cross validation of the monoclonal antibody Das-1 in identification of high-risk mucinous pancreatic cystic lesions
KK Das, X Geng, JW Brown, V Morales-Oyarvide… - Gastroenterology, 2019 - Elsevier
Background & Aims Although pancreatic cystic lesions (PCLs) are frequently and
incidentally detected, it is a challenge to determine their risk of malignancy. In …
incidentally detected, it is a challenge to determine their risk of malignancy. In …