New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

Mycobacterium tuberculosis infection of host cells in space and time

C Bussi, MG Gutierrez - FEMS microbiology reviews, 2019 - academic.oup.com
Tuberculosis (TB) caused by the bacterial pathogen Mycobacterium tuberculosis (Mtb)
remains one of the deadliest infectious diseases with over a billion deaths in the past 200 …

Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection

LCK Bell, M Noursadeghi - Nature Reviews Microbiology, 2018 - nature.com
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals
infected with HIV-1. It has long been known that HIV-1 infection alters the course of M …

Macrophage defense mechanisms against intracellular bacteria

G Weiss, UE Schaible - Immunological reviews, 2015 - Wiley Online Library
Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Autophagy in infection, inflammation and immunity

V Deretic, T Saitoh, S Akira - Nature Reviews Immunology, 2013 - nature.com
Autophagy is a fundamental eukaryotic pathway that has multiple effects on immunity.
Autophagy is induced by pattern recognition receptors and, through autophagic adaptors, it …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Autophagy and macrophage functions: inflammatory response and phagocytosis

MY Wu, JH Lu - Cells, 2019 - mdpi.com
Autophagy is a conserved bulk degradation and recycling process that plays important roles
in multiple biological functions, including inflammatory responses. As an important …

Modulation of inflammation by autophagy: consequences for human disease

RT Netea-Maier, TS Plantinga, FL van de Veerdonk… - Autophagy, 2016 - Taylor & Francis
Autophagy and inflammation are 2 fundamental biological processes involved in both
physiological and pathological conditions. Through its crucial role in maintaining cellular …

Mycobacterium tuberculosis: success through dormancy

M Gengenbacher, SHE Kaufmann - FEMS microbiology reviews, 2012 - academic.oup.com
Tuberculosis (TB) remains a major health threat, killing nearly 2 million individuals around
this globe, annually. The only vaccine, developed almost a century ago, provides limited …

TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation

M Pilli, J Arko-Mensah, M Ponpuak, E Roberts… - Immunity, 2012 - cell.com
Autophagy is a fundamental biological process of the eukaryotic cell contributing to diverse
cellular and physiological functions including cell-autonomous defense against intracellular …