Predictive value of the 4Ts scoring system for heparin-induced thrombocytopenia: a systematic review and meta-analysis

A Cuker, PA Gimotty, MA Crowther… - Blood, The Journal of …, 2012 - ashpublications.org
The 4Ts is a pretest clinical scoring system for heparin-induced thrombocytopenia (HIT).
Although widely used in clinical practice, its predictive value for HIT in diverse settings and …

Heparin-induced thrombocytopenia: a comprehensive clinical review

BS Salter, MM Weiner, MA Trinh, J Heller… - Journal of the American …, 2016 - jacc.org
Heparin-induced thrombocytopenia is a profoundly dangerous, potentially lethal,
immunologically mediated adverse drug reaction to unfractionated heparin or, less …

Thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination

A Greinacher, T Thiele, TE Warkentin… - … England Journal of …, 2021 - Mass Medical Soc
Background Several cases of unusual thrombotic events and thrombocytopenia have
developed after vaccination with the recombinant adenoviral vector encoding the spike …

Pathologic antibodies to platelet factor 4 after ChAdOx1 nCoV-19 vaccination

M Scully, D Singh, R Lown, A Poles… - … England Journal of …, 2021 - Mass Medical Soc
Background The mainstay of control of the coronavirus disease 2019 (Covid-19) pandemic
is vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Frequency of positive anti-PF4/polyanion antibody tests after COVID-19 vaccination with ChAdOx1 nCoV-19 and BNT162b2

T Thiele, L Ulm, S Holtfreter… - Blood, The Journal …, 2021 - ashpublications.org
Vaccination using the adenoviral vector COVID-19 vaccine ChAdOx1 nCoV-19
(AstraZeneca) has been associated with rare vaccine-induced immune thrombotic …

Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein

A Greinacher, K Selleng, J Mayerle… - Blood, The Journal …, 2021 - ashpublications.org
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe adverse effect of
ChAdOx1 nCoV-19 COVID-19 vaccine (Vaxzevria) and Janssen Ad26. COV2. S COVID-19 …

[HTML][HTML] A prothrombotic thrombocytopenic disorder resembling heparin-induced thrombocytopenia following coronavirus-19 vaccination

A Greinacher, T Thiele, TE Warkentin, K Weisser… - 2021 - europepmc.org
Background:. Vaccines are important for managing the COVID-19 pandemic caused by
SARS-CoV-2. However, following widespread vaccination using a recombinant adenoviral …

Treatment and prevention of heparin-induced thrombocytopenia: American College of Chest Physicians evidence-based clinical practice guidelines

TE Warkentin, A Greinacher, A Koster, AM Lincoff - Chest, 2008 - Elsevier
This chapter about the recognition, treatment, and prevention of heparin-induced
thrombocytopenia (HIT) is part of the Antithrombotic and Thrombolytic Therapy: American …

Thrombocytopenia and splenic platelet-directed immune responses after IV ChAdOx1 nCov-19 administration

L Nicolai, A Leunig, K Pekayvaz… - Blood, The Journal …, 2022 - ashpublications.org
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are
based on a range of novel platforms, with adenovirus-based approaches (like ChAdOx1 …

A flow cytometric assay to detect platelet-activating antibodies in VITT after ChAdOx1 nCov-19 vaccination

S Handtke, M Wolff, C Zaninetti… - Blood, The Journal …, 2021 - ashpublications.org
Vaccination is crucial in combatting the severe acute respiratory syndrome coronavirus 2
pandemic. The rare complication of thrombocytopenia and thrombotic complications at …