Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

[HTML][HTML] Endometriosis: advances and controversies in classification, pathogenesis, diagnosis, and treatment

E Rolla - F1000Research, 2019 - ncbi.nlm.nih.gov
Endometriosis is an enigmatic disease that could start at birth. Its pathogenesis is supported
by different theories. Accumulating facts relate it to a multigenic disorder. In this review of …

Cancer-associated mutations in endometriosis without cancer

MS Anglesio, N Papadopoulos, A Ayhan… - … England Journal of …, 2017 - Mass Medical Soc
Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic …

[HTML][HTML] Pathogenesis of endometriosis: the genetic/epigenetic theory

PR Koninckx, A Ussia, L Adamyan, A Wattiez… - Fertility and sterility, 2019 - Elsevier
Objective To study the pathophysiology of endometriosis. Design Overview of observations
on endometriosis. Setting Not applicable. Patient (s) None. Interventions (s) None. Main …

Endometrial stem/progenitor cells: the first 10 years

CE Gargett, KE Schwab… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND The existence of stem/progenitor cells in the endometrium was postulated
many years ago, but the first functional evidence was only published in 2004. The …

[HTML][HTML] Pathogenesis and pathophysiology of endometriosis

RO Burney, LC Giudice - Fertility and sterility, 2012 - Elsevier
Originally described over three hundred years ago, endometriosis is classically defined by
the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is …

Endometriosis

SE Bulun, BD Yilmaz, C Sison, K Miyazaki… - Endocrine …, 2019 - academic.oup.com
Pelvic endometriosis is a complex syndrome characterized by an estrogen-dependent
chronic inflammatory process that affects primarily pelvic tissues, including the ovaries. It is …

Theories on the pathogenesis of endometriosis

S Sourial, N Tempest… - International journal of …, 2014 - Wiley Online Library
Endometriosis is a common, chronic inflammatory disease defined by the presence of
extrauterine endometrial tissue. The aetiology of endometriosis is complex and …

Pathophysiology and immune dysfunction in endometriosis

SH Ahn, SP Monsanto, C Miller… - BioMed research …, 2015 - Wiley Online Library
Endometriosis is an estrogen‐dependent, chronic, proinflammatory disease prevalent in
10% of women of reproductive age worldwide. Characterized by the growth of endometrium …

Adenomyosis: a clinical review of a challenging gynecologic condition

J Struble, S Reid, MA Bedaiwy - Journal of minimally invasive gynecology, 2016 - Elsevier
Adenomyosis is a heterogenous gynecologic condition. Patients with adenomyosis can
have a range of clinical presentations. The most common presentation of adenomyosis is …