Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver
disease worldwide and is strongly associated with the presence of oxidative stress …

The molecular mechanisms of sodium-glucose cotransporter-2 (SGLT2) inhibitors (SGLT2i)
remain incompletely understood. Single-cell RNA sequencing and morphometric data were …

Mitochondrial fatty acid β-oxidation (FAO) is the major pathway for the degradation of fatty
acids and is essential for maintaining energy homeostasis in the human body. Fatty acids …

Mitochondrial fatty acid oxidation is an essential pathway for energy production, especially
during prolonged fasting and sub-maximal exercise. Long-chain fatty acids are the most …

Over the years, the mitochondrial fatty acid β-oxidation (FAO) pathway has been
characterised at the biochemical level as well as the molecular biological level. FAO plays a …

Carnitine plays an essential role in mitochondrial fatty acid β-oxidation as a part of a cycle
that transfers long-chain fatty acids across the mitochondrial membrane and involves two …

Electron transfer flavoprotein (ETF) is an enzyme with orthologs from bacteria to humans.
Human ETF is nuclear encoded by two separate genes, ETFA and ETFB, respectively. After …

Peroxisomes are essential organelles for the specialized oxidation of a wide variety of fatty
acids, but they are also able to degrade fatty acids that are typically handled by …

Oxidation of fatty acids in mitochondria is a key physiological process in higher eukaryotes
including humans. The importance of the mitochondrial beta-oxidation system in humans is …