Suicide and suicide risk

G Turecki, DA Brent, D Gunnell, RC O'Connor… - Nature reviews Disease …, 2019 - nature.com
Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …

[HTML][HTML] Advancing a temporal framework for understanding the biology of nonsuicidal self-injury: An expert review

M Kaess, JM Hooley, B Klimes-Dougan… - Neuroscience & …, 2021 - Elsevier
Nonsuicidal self-injury (NSSI) is a serious clinical problem, particularly for adolescents and
young adults. NSSI is a complex behavior that emerges through the intersecting effects of …

Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in> 1.2 million individuals highlight new therapeutic directions

DF Levey, MB Stein, FR Wendt, GA Pathak… - Nature …, 2021 - nature.com
Major depressive disorder is the most common neuropsychiatric disorder, affecting 11% of
veterans. Here we report results of a large meta-analysis of depression using data from the …

[HTML][HTML] Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders, and known risk factors

N Mullins, JE Kang, AI Campos, JRI Coleman… - Biological …, 2022 - Elsevier
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts,
which occur far more frequently, are a major source of disability and social and economic …

Genome-wide association study meta-analysis of suicide death and suicidal behavior

QS Li, AA Shabalin, E DiBlasi, S Gopal… - Molecular …, 2023 - nature.com
Suicide is a worldwide health crisis. We aimed to identify genetic risk variants associated
with suicide death and suicidal behavior. Meta-analysis for suicide death was performed …

Socioeconomic deprivation index is associated with psychiatric disorders: an observational and genome-wide gene-by-environment interaction analysis in the UK …

J Ye, Y Wen, X Sun, X Chu, P Li, B Cheng, S Cheng… - Biological …, 2021 - Elsevier
Background Psychiatric disorders are among the largest and fastest-growing categories of
the global disease burden. However, limited effort has been made to further elucidate …

On the genetic and environmental relationship between suicide attempt and death by suicide

AC Edwards, H Ohlsson, E Mościcki… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: The authors examined the extent to which the genetic and environmental etiology
of suicide attempt and suicide death is shared or unique. Methods: The authors used …

Genetic contributions to suicidal thoughts and behaviors

E DiBlasi, J Kang, AR Docherty - Psychological medicine, 2021 - cambridge.org
Suicidal ideation, suicide attempt (SA) and suicide are significantly heritable phenotypes.
However, the extent to which these phenotypes share genetic architecture is unclear. This …

Identifying behaviour-related and physiological risk factors for suicide attempts in the UK Biobank

B Zhang, J You, ET Rolls, X Wang, J Kang, Y Li… - Nature human …, 2024 - nature.com
Suicide is a global public health challenge, yet considerable uncertainty remains regarding
the associations of both behaviour-related and physiological factors with suicide attempts …

Identification of novel, replicable genetic risk loci for suicidal thoughts and behaviors among US military veterans

NA Kimbrel, AE Ashley-Koch, XJ Qin… - JAMA …, 2023 - jamanetwork.com
Importance Suicide is a leading cause of death; however, the molecular genetic basis of
suicidal thoughts and behaviors (SITB) remains unknown. Objective To identify novel …