Medical therapy for glaucoma: A review

RJ Casson - Clinical & Experimental Ophthalmology, 2022 - Wiley Online Library
A number of pharmacological targets are exploited to modify the parameters in the
Goldmann equation and reduce the intraocular pressure (IOP). This strategy constitutes the …

Pharmacological and ocular hypotensive properties of topical carbonic anhydrase inhibitors

MF Sugrue - Progress in retinal and eye research, 2000 - Elsevier
There was a time gap of over 40 years between the demonstrated oral effectiveness of
acetazolamide in lowering the intraocular pressure (IOP) of glaucoma patients and the …

Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension

G Fuchsjäger-Mayrl, B Wally… - … & visual science, 2004 - iovs.arvojournals.org
purpose. There is evidence that altered optic nerve head (ONH) blood flow may play a role
in the development and progression of glaucoma. In the present study, the baseline …

Use of colour Doppler imaging in ocular blood flow research

I Stalmans, E Vandewalle, DR Anderson… - Acta …, 2011 - Wiley Online Library
The main objective of this report is to encourage consistent quality of testing and reporting
within and between centres that use colour Doppler imaging (CDI) for assessment of …

[HTML][HTML] Neuroprotection in glaucoma

A Doozandeh, S Yazdani - Journal of ophthalmic & vision research, 2016 - ncbi.nlm.nih.gov
Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC)
loss and visual field defects. It is known that in some glaucoma patients, death of RGCs …

[HTML][HTML] Twenty-four hour ocular perfusion pressure fluctuation and risk of normal-tension glaucoma progression

KR Sung, S Lee, SB Park, J Choi, ST Kim… - … & visual science, 2009 - arvojournals.org
Purpose.: To investigate the relationship between clinical factors including 24-hour mean
ocular perfusion pressure (MOPP, ⅔× mean arterial pressure [MAP]− intraocular pressure …

Predictive value of colour Doppler imaging in a prospective study of visual field progression in primary open‐angle glaucoma

A Martínez, M Sánchez - Acta Ophthalmologica Scandinavica, 2005 - Wiley Online Library
Purpose: To assess the value of colour Doppler imaging (CDI) of the ophthalmic artery (OA)
and short posterior ciliary arteries (SPCAs) in prognosis of disease progression in patients …

A review of potential novel glaucoma therapeutic options independent of intraocular pressure

WS Shalaby, OM Ahmed, M Waisbourd, LJ Katz - Survey of Ophthalmology, 2022 - Elsevier
Glaucoma, a progressive optic neuropathy characterized by retinal ganglion cell
degeneration and visual field loss, is the leading cause of irreversible blindness worldwide …

The effects of antiglaucoma and systemic medications on ocular blood flow

VP Costa, A Harris, E Stefánsson, J Flammer… - Progress in retinal and …, 2003 - Elsevier
Based on the body of evidence implicating ocular blood flow disturbances in the
pathogenesis of glaucoma, there is great interest in the investigation of the effects of …

The European glaucoma prevention study design and baseline description of the participants

European Glaucoma Prevention Study (EGPS) Group - Ophthalmology, 2002 - Elsevier
OBJECTIVES: The European Glaucoma Prevention Study seeks to evaluate the efficacy of
reducing intraocular pressure (IOP), with dorzolamide to prevent or delay patients affected …