Histone demethylases remove transcriptional repressive marks from histones in the nucleus. KDM6A (also known as UTX) is a lysine demethylase which acts on the trimethylated lysine …
K Prasad, SY AlOmar, SAM Alqahtani, MZ Malik… - Molecular …, 2021 - Springer
Although COVID-19 largely causes respiratory complications, it can also lead to various extrapulmonary manifestations resulting in higher mortality and these comorbidities are …
Turner syndrome (TS), a genetic disorder due to incomplete dosage compensation of X- linked genes, affects multiple organ systems, leading to hypogonadotropic hypogonadism …
Lung cancer is one of the most invasive cancers affecting over a million of the population. Non-small cell lung cancer (NSCLC) constitutes up to 85% of all lung cancer cases, and …
Curcumin is a natural anti-inflammatory and antioxidant substance which plays a major role in reducing the amyloid plaques formation, which is the major cause of Alzheimer's disease …
Complex disease networks can be studied successfully using network theoretical approach which helps in finding key disease genes and associated disease modules. We studied …
Network medicine provides network theoretical tools, methods and properties to study underlying laws governing human interactome to identify disease states and disease …
Breast cancer is one of the most prevalent types of cancer diagnosed globally and continues to have a significant impact on the global number of cancer deaths. Despite all efforts of …
Background Identification of key regulator/s in ovarian cancer (OC) network is important for potential drug target and prevention from this cancer. This study proposes a method to …