γ‐Aminobutyric acid (GABA) is synthesized in brain in at least two compartments, commonly
called the transmitter and metabolic compartments, and because reglatory processes must …

One of the primary approaches in experimental brain research is to investigate the effects of
specific destruction of its parts. Here, several neurotoxins are available which can be used to …

Rats sustaining unilateral near‐complete 6‐hydroxydopamine lesions of the mesostriatal
dopamine pathway received daily injections of 3, 4 dihydroxyphenyl‐l‐alanine (L‐DOPA, 8 …

Cells expressing mRNA for hippocampus-derived neurotrophic factor (HDNWNT-3) or
brainderived neurotrophic factor (BDNF) were identified by in situ hybridization. In the rat …

Neurocircuit inhibition of hypothalamic paraventricular nucleus (PVN) neurons controlling
hypothalamo–pituitary–adrenocortical (HPA) activity prominently involves GABAergic cell …

The expression of the genes encoding the alpha subunit of type II calcium calmodulin-
dependent protein kinase (CaM II kinase α) and the 67,000 mol. wt form of glutamic acid …

Nonradioactive in situ hybridization methods with digoxigenin‐labeled cRNA probes were
used to localize two glutamic acid decarboxylase (GAD) mRNAs in rat brain. These mRNAs …

Dopamine afferents to the cortex regulate the excitability of pyramidal neurons via a direct
synaptic input. However, it has not been established whether dopamine also modulates …

This review covers some recent findings of the electrophysiological mechanisms through
which mesocortical dopamine modulates prefrontal cortical neurons. Dopamine has been …

Destruction of the dopamine-containing neurons in the rat substantia nigra results in
morphological changes in the striatum which have been characterized at both the light and …