'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr …

S Jarius, B Wildemann - Journal of neuroinflammation, 2015 - Springer
Serological testing for anti-neural autoantibodies is important in patients presenting with
idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine …

Non-canonical signaling, the hidden life of ligand-gated ion channels

S Valbuena, J Lerma - Neuron, 2016 - cell.com
Neurotransmitter receptors are responsible for the transfer of information across the
synapse. While ionotropic receptors form ion channels and mediate rapid membrane …

Purkinje cell signaling deficits in animal models of ataxia

E Hoxha, I Balbo, MC Miniaci, F Tempia - Frontiers in synaptic …, 2018 - frontiersin.org
Purkinje cell (PC) dysfunction or degeneration is the most frequent finding in animal models
with ataxic symptoms. Mutations affecting intrinsic membrane properties can lead to ataxia …

A GluD coming-of-age story

M Yuzaki, AR Aricescu - Trends in neurosciences, 2017 - cell.com
The GluD1 and GluD2 receptors form the GluD ionotropic glutamate receptor (iGluR)
subfamily. Without known endogenous ligands, they have long been referred to as …

GRID2 mutations span from congenital to mild adult-onset cerebellar ataxia

M Coutelier, L Burglen, E Mundwiller… - Neurology, 2015 - AAN Enterprises
Objectives: In a large family of Algerian origin, we aimed to identify the genetic mutation
segregating with simultaneous presence of adult-onset, paucisymptomatic, slowly …

[HTML][HTML] TRP Channels in the Brain

S Sawamura, H Shirakawa, T Nakagawa… - Neurobiology of TRP …, 2017 - ncbi.nlm.nih.gov
Transient receptor potential (TRP) family proteins form tetrameric nonselective cation
channels. Upon activation, TRP channels depolarize the membrane potential, which can …

'Medusa head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca …

S Jarius, B Wildemann - Journal of neuroinflammation, 2015 - Springer
Serological testing for anti-neural autoantibodies is important in patients presenting with
idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine …

Essential tremor–a cerebellar driven disorder?

MF Ibrahim, JC Beevis, RM Empson - Neuroscience, 2021 - Elsevier
Abnormal tremors are the most common of all movement disorders. In this review we focus
on the role of the cerebellum in Essential Tremor, a highly debilitating but poorly treated …

Long-term depression and other synaptic plasticity in the cerebellum

T Hirano - Proceedings of the Japan Academy, Series B, 2013 - jstage.jst.go.jp
Cerebellar long-term depression (LTD) is a type of synaptic plasticity and has been
considered as a critical cellular mechanism for motor learning. LTD occurs at excitatory …

mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease

M Yamasaki, A Aiba, M Kano, M Watanabe - Neuropharmacology, 2021 - Elsevier
The cerebellum is essential for the control, coordination, and learning of movements, and for
certain aspects of cognitive function. Purkinje cells are the sole output neurons in the …