Molecular pharmacology and therapeutic advances of the pentacyclic triterpene lupeol

AAM Sohag, MT Hossain, MA Rahaman, P Rahman… - Phytomedicine, 2022 - Elsevier
Background Plant triterpenoids are major sources of nutraceuticals that provide many health
benefits to humans. Lupeol is one of the pentacyclic dietary triterpenoids commonly found in …

Exploring the Therapeutic Potential of Lupeol: A Review of Its Mechanisms, Clinical Applications, and Advances in Bioavailability Enhancement

X Luo, J Li, Z Cen, G Feng, M Hong, L Huang… - Food and Chemical …, 2024 - Elsevier
Lupeol, a naturally occurring triterpenoid, has garnered significant attention for its diverse
range of biological activities and potential therapeutic applications. This comprehensive …

Anti-metastatic effects of lupeol via the inhibition of MAPK/ERK pathway in lung cancer

M Bhatt, M Patel, M Adnan… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
Background and Objective: ERK pathway is one of the most crucial pathways in lung cancer
metastasis. Targeting its pathway is decisive in lung cancer research. Thus, this study …

Tokoronin Contained in Dioscorea tokoro Makino ex Miyabe Suppressed α‐MSH‐Induced Melanogenesis in B16 Cells via Suppression of Classical MAPK Pathway …

M Ukiya, D Sato, H Kimura, Y Hirai… - Chemistry & …, 2020 - Wiley Online Library
In this study, melanogenesis inhibition in B16 cells by eight compounds, namely,
tokorogenin, tokoronin, yononin, gracillin, proto‐yonogenin, proto‐tokoronin, proto‐yononin …

Inhibition of metastasis and suppression of pERK1/2 and pFAK expression by Solanum xanthocarpum crude extracts in human lung cancer cell line A549 in vitro

MN Reddy, M Bhatt - Indian Journal of Natural Products and …, 2021 - op.niscpr.res.in
Solanum xanthocarpum is an important part of natural remedies for lung in Ayurveda. Lung
cancer metastasis is a major challenge in the present time. Expressions and activation of …

Antimetastatic, superoxide anion and nitric oxide reduction potential of Solanum xanthocarpum on human lung cancer cell line A549

M Bhatt, MN Reddy - 2018 - nopr.niscpr.res.in
Solanum xanthocarpum Schrad. & H. Wendl is a prickly herb, extensively known for its
medicinal properties across the tribal and rural parts of India. Its efficacy in lung disorders …

In silico docking of phytochemicals from Indigofera aspalathoides to identify potent inhibitors of MAP kinase.

CS Sundaram, L Krishnasamy… - Pakistan Journal of …, 2022 - search.ebscohost.com
In the present article, around 40 compounds from Indigofera aspalathoides were screened
for inhibition of MAP Kinase, as mitogen-activated protein Kinase plays a vital role in many …

[PDF][PDF] A molecular docking mechanism model for benzimidazole to inactivate glutathione reductase in chickpea

G Singh, M Kaur - Online J. Bioinform, 2019 - researchgate.net
ABSTRACT Singh G, Kaur M., A molecular docking mechanism model for benzimidazole to
inactivate glutathione reductase in chickpea., Onl J Bioinform., 20 (2):, 2019 …

Phytochemical and Pharmacological Aspects of Hygrophila Spinosa: An Overview

S Gaikwad, L Kothapalli, A Thomas - Current Indian Science, 2023 - benthamdirect.com
Background A plant from the Acanthaceae family, Hygrophila spinosa T. Ander is
geographically distributed throughout Asia and is noted for its diuretic and aphrodisiac …

In-Silico Interaction of Hydroxychloroquine Drug with Various Proteins of Coronavirus (SARS-CoV-2): A Computational Approaches to Combat COVID-19

R Kalaria, HK Patel - 2020 - chemrxiv.org
In silico docking study showed that hydroxychloroquine drug interactions with SARS-CoV2
show a higher binding affinity with spike glycoprotein and PLPRO protein compared to …