Recent advances in colon drug delivery systems

R Arévalo-Pérez, C Maderuelo, JM Lanao - Journal of Controlled Release, 2020 - Elsevier
As a result of its ability to target certain drugs and/or peptides to the colonic region for the
treatment of several diseases while avoiding systemic absorption and potential side effects …

Drug carrier for photodynamic cancer therapy

TA Debele, S Peng, HC Tsai - International journal of molecular sciences, 2015 - mdpi.com
Photodynamic therapy (PDT) is a non-invasive combinatorial therapeutic modality using
light, photosensitizer (PS), and oxygen used for the treatment of cancer and other diseases …

Impact of gastric pH variations on the release of amorphous solid dispersion formulations containing a weakly basic drug and enteric polymers

HT Nguyen, T Van Duong, LS Taylor - Molecular Pharmaceutics, 2023 - ACS Publications
Enteric polymers are widely used in amorphous solid dispersion (ASD) formulations. The
aim of the current study was to explore ASD failure mechanisms across a wide range of pH …

Boosting 3-acetamido-5-acetylfuran production from N-acetyl-D-glucosamine in γ-valerolactone by a dissolution-dehydration effect

X Ji, J Kou, G Gözaydın, X Chen - Applied Catalysis B: Environmental, 2024 - Elsevier
Chitin biorefinery offers a unique opportunity to sustainably produce highly-valued
organonitrogen compounds such as the versatile pharmaceutical precursor 3-acetamido-5 …

Photo‐crosslinked poly (ethylene glycol) diacrylate (PEGDA) hydrogels from low molecular weight prepolymer: swelling and permeation studies

A Cavallo, M Madaghiele, U Masullo… - Journal of Applied …, 2017 - Wiley Online Library
The aim of this work was to assess the diffusive properties of poly (ethylene glycol)
diacrylate (PEGDA)‐based hydrogels, derived from low MW prepolymers, in view of …

Methodology of oral formulation selection in the pharmaceutical industry

M Kuentz, R Holm, DP Elder - European Journal of Pharmaceutical …, 2016 - Elsevier
Pharmaceutical formulations have to fulfil various requirements with respect to their intended
use, either in the development phase or as a commercial product. New drug candidates with …

Smart freeze-dried bigels for the prevention of the sexual transmission of HIV by accelerating the vaginal release of tenofovir during intercourse

A Martín-Illana, F Notario-Pérez, R Cazorla-Luna… - Pharmaceutics, 2019 - mdpi.com
Sub-Saharan African women are still at risk from the human immunodeficiency virus (HIV),
and sex with men is the main route of transmission. Vaginal formulations containing …

Thermogelling Hydroxypropyl Methylcellulose Nanoemulsions as Templates to Formulate Poorly Water-Soluble Drugs into Oral Thin Films Containing Drug …

LH Chen, PS Doyle - Chemistry of Materials, 2022 - ACS Publications
Oral thin films are an emerging solid dosage form for the delivery of poorly water-soluble
drugs. Typical thin film formulations require nanomilling of drugs to improve their poor water …

Zein as a pharmaceutical excipient in oral solid dosage forms: state of the art and future perspectives

A Berardi, L Bisharat, HS AlKhatib, M Cespi - Aaps Pharmscitech, 2018 - Springer
Zein is the main storage protein of corn and it has several industrial applications. Mainly in
the last 10–15 years, zein has emerged as a potential pharmaceutical excipient with unique …

Preparation, stability and controlled release properties of starch-based micelles for oral delivery of hydrophobic bioactive molecules

Y Zhang, K Liu, C Chi, L Chen, X Li - International Journal of Biological …, 2024 - Elsevier
Amphiphilic starches incorporating fatty acid ester chains of varying lengths and degrees of
substitution (DS) were synthesized to fabricate starch-based micelles for oral delivery of …