Epithelial cells display dynamic behaviours, such as rearrangement, movement and shape
changes, particularly during embryonic development and in equivalent processes in adults …

During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …

During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs)
ensure intercellular adhesion and tissue integrity while allowing for cell and tissue …

Classical cadherins are transmembrane proteins at the core of intercellular adhesion
complexes in cohesive metazoan tissues. The extracellular domain of classical cadherins …

The development and maintenance of tissues requires collective cell movement, during
which neighbouring cells coordinate the polarity of their migration machineries. Here, we …

Cadherins are the principal adhesion proteins at intercellular junctions and function as the
biochemical Velcro that binds cells together. Besides this mechanical function, cadherin …

During evolution from primitive species, a mechanism, termed epithelial-mesenchymal
transition (EMT), was established to create mesenchymal cells from a pre-existing epithelial …

To remodel endothelial cell–cell adhesion, inflammatory cytokine-and angiogenic growth
factor–induced signals impinge on the vascular endothelial cadherin (VE-cadherin) …

Epithelial and endothelial monolayers are multicellular sheets that form barriers between the
'outside'and 'inside'of tissues. Cell-cell junctions, made by adherens junctions, tight junctions …

Cadherins are transmembrane proteins that mediate cell–cell adhesion in animals. By
regulating contact formation and stability, cadherins play a crucial role in tissue …