It is known that feasible regular muscle training of an aerobic nature helps to reduce platelet
activity of people with high normal blood pressure. At the same time, the physiological …

In the normal course of the delivery of care, anesthesiologists encounter many patients who
are receiving drugs that affect platelet function as a fundamental part of primary and …

Oral antiplatelet drugs are a cornerstone of modern pharmacotherapy in cardiovascular
atherothrombotic diseases. The efficacy of acetylsalicylic acid (ASA, aspirin) and clopidogrel …

ADP and ATP play a crucial role in platelet activation and their receptors are potential
targets for antithrombotic drugs. The ATP-gated cation channel P2X 1 and the two G protein …

Aspirin is well recognized as an effective antiplatelet drug for secondary prevention in
subjects at high risk of cardiovascular events. However, most patients receiving long-term …

Emerging studies highlight high on-treatment of platelet reactivity (HTPR) as a major
hindrance to the secondary prevention of cardiovascular ischemic events. The aim of this …

Myocardial infarction, commonly known as heart attack, evolves from the rupture of unstable
atherosclerotic plaques to coronary thrombosis and myocardial ischemia–reperfusion injury …

BACKGROUND: Hyperuricemia may be involved in the atherosclerotic process due to
endothelial dysfunction and facilitation of smooth muscle cell proliferation. However …

Objectives: The purpose of this study was to investigate the long-term outcome after elective
percutaneous coronary intervention in low-risk patients screened for aspirin and/or …

While the importance of cyclooxygenase (COX) in platelet function has been amply
elucidated, the identification of the role of 12-lipoxygenase (12-LOX) and of its stable …