Tuberculosis of the central nervous system (CNS) is a highly devastating form of
tuberculosis, which, even in the setting of appropriate antitubercular therapy, leads to …

Central nervous system (CNS) tuberculosis, particularly tuberculous meningitis (TBM), is the
severest form of Mycobacterium tuberculosis (M. Tb) infection, causing death or severe …

Rapid and specific diagnosis of tubercular meningitis is of paramount importance to
decrease morbidity and mortality. The aim of the study was to evaluate multiplex PCR using …

Background Tuberculous meningitis (TBM) is one of the common clinical manifestations of
extra-pulmonary tuberculosis. It is difficult to diagnose due to a lack of rapid, sensitive, and …

In recent years, the number of cases of extrapulmonary tuberculosis in Iran has increased.
The goal of this study was to determine the epidemiological status, clinical symptoms …

Although nucleic acid amplification tests (NAATs) promise a rapid, definitive diagnosis of
tuberculous meningitis, the performance of first-generation NAATs was suboptimal and …

A PCR was standardized for amplifying three different mycobacterial—IS6110, MPB-64, 65
kDa DNA sequences. A comparative evaluation of the three PCR assays was carried out for …

Tuberculous meningitis (TBM) remains a common serious neurological emergency—
especially in the developing world. Elevated intracranial pressure (ICP) is often a feature of …

Abstract Purpose Multiplex Polymerase Chain Reaction (MPCR) is a technique in which two
or more gene targets are amplified in a single reaction. This has increased sensitivity of …

Background: Rapid and specific diagnosis of tubercular meningitis (TBM) is of utmost
importance. Aim: To evaluate polymerase chain reaction (PCR) using protein b primers …