Catalysts of Healing: A Symphony of Synthesis and Clinical Artistry in Small-Molecule Agents for Breast Cancer Alleviation

J Hu, BY Zhu, ZX Niu - Molecules, 2024 - mdpi.com
Breast cancer, characterized by its molecular intricacy, has witnessed a surge in targeted
therapeutics owing to the rise of small-molecule drugs. These entities, derived from cutting …

Isethionate salt of a selective CKD4 inhibitor

VG Beylin, AC Blackburn, DT Erdman… - US Patent …, 2008 - Google Patents
US7345171B2 - Isethionate salt of a selective CKD4 inhibitor - Google Patents US7345171B2 -
Isethionate salt of a selective CKD4 inhibitor - Google Patents Isethionate salt of a selective …

Pharmaceutical Combinations of Diazole Derivatives for Cancer Treatment

MS Squires - US Patent App. 12/300,056, 2009 - Google Patents
0* N ([3*]) C (= O) C1= NNC= C1N (*) C ([1*])= O.[4*] S (= O)(= O) N1CCC (C) CC1 Chemical
compound* N ([3*]) C (= O) C1= NNC= C1N (*) C ([1*])= O.[4*] S (= O)(= O) N1CCC (C) CC1 …

Inhibitors of the fibroblast growth factor receptor

N Bifulco, LV DiPietro, BL Hodous… - US Patent …, 2019 - Google Patents
US10221154B2 - Inhibitors of the fibroblast growth factor receptor - Google Patents
US10221154B2 - Inhibitors of the fibroblast growth factor receptor - Google Patents Inhibitors of …

Inhibitors of the fibroblast growth factor receptor

N Bifulco, LV DiPietro, CV Miduturu - US Patent 10,000,490, 2018 - Google Patents
US10000490B2 - Inhibitors of the fibroblast growth factor receptor - Google Patents
US10000490B2 - Inhibitors of the fibroblast growth factor receptor - Google Patents Inhibitors of …

HSPC-sparing treatments for RB-positive abnormal cellular proliferation

JC Strum, JE Bisi, PJ Roberts, FX Tavares - US Patent 9,527,857, 2016 - Google Patents
2016-06-06 Assigned to G1 THERAPEUTICS, INC. reassignment G1 THERAPEUTICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Transient protection of normal cells during chemotherapy

JC Strum, JE Bisi, PJ Roberts, FX Tavares - US Patent 9,487,530, 2016 - Google Patents
2016-05-26 Assigned to G1 THERAPEUTICS, INC. reassignment G1 THERAPEUTICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Pharmaceutical Compounds

JE Curry, JF Lyons, MS Squires… - US Patent App. 11 …, 2009 - Google Patents
2008-03-05 Assigned to ASTEX THERAPEUTICS LIMITED reassignment ASTEX
THERAPEUTICS LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Pyrido [2, 3-d] pyrimidine-2, 7-diamine kinase inhibitors

RJ Booth, EM Dobrusin, VPVN Josyula… - US Patent …, 2006 - Google Patents
This invention relates to pyrido 2, 3-dipyrimidine-2.7-kinases. Thus, these compounds are
useful to treat cell diamines that inhibit cyclin-dependent serine/threonine proliferative …

Inhibitors of the fibroblast growth factor receptor

CV Miduturu - US Patent 10,196,436, 2019 - Google Patents
514/303 9, 034, 898 B2 5/2015 Clary-Ceccato et al. 9, 126, 951 B2* 9/2015 Bifulco, Jr...........
CO7D 239/42 9, 200, 002 B2 12/2015 Hodous et al. 9, 266, 883 B2 2/2016 Buschmann et al …