Remnant nephron physiology and the progression of chronic kidney disease
HW Schnaper - Pediatric nephrology, 2014 - Springer
In chronic kidney disease, ongoing failure of individual nephrons leads to the progressive
loss of renal function. This process results in part from a cellular and molecular response to …
loss of renal function. This process results in part from a cellular and molecular response to …
[HTML][HTML] Microarray analysis of gene expression in fibrovascular membranes excised from patients with proliferative diabetic retinopathy
K Ishikawa, S Yoshida, Y Kobayashi… - … & visual science, 2015 - tvst.arvojournals.org
Methods.: Six FVMs were surgically removed from patients with proliferative diabetic
retinopathy (PDR) during pars plana vitrectomy with membrane peeling. The FVMs were …
retinopathy (PDR) during pars plana vitrectomy with membrane peeling. The FVMs were …
C5a induces the synthesis of IL-6 and TNF-α in rat glomerular mesangial cells through MAPK signaling pathways
M Ji, Y Lu, C Zhao, W Gao, F He, J Zhang, D Zhao… - PLoS …, 2016 - journals.plos.org
Inflammatory response has been reported to contribute to the renal lesions in rat Thy-1
nephritis (Thy-1N) as an animal model of human mesangioproliferative glomerulonephritis …
nephritis (Thy-1N) as an animal model of human mesangioproliferative glomerulonephritis …
Sublytic C5b-9 triggers glomerular mesangial cell apoptosis via XAF1 gene activation mediated by p300-dependent IRF-1 acetylation
W Qiu, J Zhou, G Zhu, D Zhao, F He, J Zhang… - Cell death & …, 2014 - nature.com
The apoptosis of glomerular mesangial cells (GMCs) in rat Thy-1 nephritis (Thy-1N), a model
of human mesangioproliferative glomerulonephritis (MsPGN), is accompanied by sublytic …
of human mesangioproliferative glomerulonephritis (MsPGN), is accompanied by sublytic …
Rapamycin inhibits transforming growth factor β‐induced peritoneal angiogenesis by blocking the secondary hypoxic response
Y Sekiguchi, J Zhang, S Patterson, L Liu… - Journal of cellular …, 2012 - Wiley Online Library
Patients with end‐stage kidney disease on peritoneal dialysis often develop progressive
scarring of the peritoneal tissues. This manifests as submesothelial thickening and is …
scarring of the peritoneal tissues. This manifests as submesothelial thickening and is …
[HTML][HTML] Adenovirus-mediated gene transfer of TGF-β1 to the renal glomeruli leads to proteinuria
The mechanism of proteinuria in many common kidney diseases involves glomerular
hemodynamic effects and local expression of angiogenic, fibrogenic, and vasoactive factors …
hemodynamic effects and local expression of angiogenic, fibrogenic, and vasoactive factors …
Effects and mechanisms of angiotensin II receptor blockade with telmisartan in a normotensive model of mesangioproliferative nephritis
Background. Renoprotective actions of angiotensin receptor blockers are not well
established in normotensive, low-grade proteinuric glomerular diseases. We examined the …
established in normotensive, low-grade proteinuric glomerular diseases. We examined the …
Urinary excretion of angiogenesis regulatory factors and renal injury markers in chronic glomerulonephritis: Significance in the assessment of progression
MY Shvetsov, A Zheng, LV Kozlovskaya… - Terapevticheskii …, 2015 - journals.eco-vector.com
Aim. To study the urinary excretion of the molecular factors regulating angiogenesis, such as
vascular endothelial growth factor type A (VEGF-A), thrombospondin 1 (THBS1), and …
vascular endothelial growth factor type A (VEGF-A), thrombospondin 1 (THBS1), and …
Мочевая экскреция факторов регуляции ангиогенеза и маркеров повреждения почек при хроническом гломерулонефрите: значение в оценке …
МЮ Швецов, Ч Аньтай, ЛВ Козловская… - Терапевтический …, 2015 - cyberleninka.ru
Цель исследования. У больных хроническим гломерулонефритом (ХГН) изучить
мочевую экскрецию молекулярных факторов, регулирующих ангиогенез—фактора …
мочевую экскрецию молекулярных факторов, регулирующих ангиогенез—фактора …