Epidermal growth factor-related peptides and their receptors in human malignancies

DS Salomon, R Brandt, F Ciardiello… - Critical reviews in …, 1995 - Elsevier
The development of cancer is due to the accumulation of multiple somatic mutations and in
some cases due to germline mutations, which occur in malignancies such as retinoblastoma …

The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: a review on 5232 patients

J Klijn, E Berns, J Foekens, PIM Schmitz - Endocrine reviews, 1992 - repub.eur.nl
Epidermal growth factor (EGF) is a 53-aminoacid polypeptide (mol wt 6.045 K) that can
influence proliferation and differentiation of a wide variety of cells (1–6). EGF as well as …

Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer

J Richard, C Sainsbury, GK Needham, JR Farndon… - The Lancet, 1987 - Elsevier
In 135 primary breast cancers, there was a significant inverse relation between epidermal-
growth-factor receptor (EGFR) and oestrogen receptor (ER) status, and a significant …

Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer.

O Dassonville, JL Formento, M Francoual… - Journal of Clinical …, 1993 - ascopubs.org
PURPOSE To determine the expression of epidermal growth factor receptor (EGFR) in head
and neck squamous cell carcinoma and to evaluate its prognostic value. MATERIALS AND …

[图书][B] The breast: comprehensive management of benign and malignant diseases

KI Bland, EM Copeland, VS Klimberg, WJ Gradishar - 2023 - books.google.com
Multidisciplinary in scope and fully up to date with the latest advances in medical oncology
and more, Bland and Copeland's The Breast, 6th Edition, covers every clinically relevant …

Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours

DE Neal, MK Bennett, RR Hall, C Marsh, PD Abel… - The Lancet, 1985 - Elsevier
The presence of epidermal-growth-factor (EGF) receptors in normal and neoplastic human
urothelium was studied in 12 control patients and in 48 patients with transitional cell …

The epidermal growth factor receptor and the prognosis of bladder cancer

DE Neal, L Sharples, K Smith, J Fennelly, RR Hall… - Cancer, 1990 - Wiley Online Library
Epidermal growth factor is found in high concentrations in urine, and its receptor (EGFr) has
been identified in certain bladder tumors. This study was performed to determine whether …

MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited …

J Filmus, MN Pollak, R Cailleau, RN Buick - Biochemical and biophysical …, 1985 - Elsevier
Epidermal growth factor (EGF) has been noted to stimulate proliferation of a variety of
normal and malignant cells including those of human breast epithelium. We report here that …

Growth factors in breast cancer

RB Dickson, ME Lippman - Endocrine reviews, 1995 - academic.oup.com
I. Regulation of Mammary Cell Growth and Apoptosis A. Hormonal control of mammary
development, proliferation, and lactational defferentation D EVELOPMENT of the normal …

Overexpression of the c-erbB-2 oncoprotein in human breast carcinomas: immunohistological assessment correlates with gene amplification

DJ Venter, S Kumar, NL Tuzi, WJ Gullick - The Lancet, 1987 - Elsevier
Amplification of the human proto-oncogene c-erbB-2 was found in 12 of 36 human breast
tumours and was associated with increased levels of expression of the c-erbB-2 protein …