Motile and non-motile (primary) cilia are nearly ubiquitous cellular organelles. The
dysfunction of cilia causes diseases known as ciliopathies. The number of reported …

The primary cilium is a hair-like surface-exposed organelle of the eukaryotic cell that
decodes a variety of signals—such as odorants, light and Hedgehog morphogens—by …

The cilium is a complex organelle, the assembly of which requires the coordination of motor-
driven intraflagellar transport (IFT), membrane trafficking and selective import of cilium …

Both the basal body and the microtubule‐based axoneme it nucleates have evolutionarily
conserved subdomains crucial for cilium biogenesis, function and maintenance. Here, we …

Cilia play many essential roles in fluid transport and cellular locomotion, and as sensory
hubs for a variety of signal transduction pathways. Despite having a conserved basic …

C. elegans has a highly developed chemosensory system that enables it to detect a wide
variety of volatile (olfactory) and water-soluble (gustatory) cues associated with food …

Cilia and flagella are ancient, evolutionarily conserved organelles that project from cell
surfaces to perform diverse biological roles, including whole-cell locomotion; movement of …

Meckel-Gruber syndrome (MKS), nephronophthisis (NPHP), and related ciliopathies present
with overlapping phenotypes and display considerable allelism between at least twelve …

Respect for the primary cilium has undergone a remarkable renaissance over the past
decade, and it is now thought to be an essential regulator of numerous signaling pathways …

Primary cilia (PC) function as microtubule-based sensory antennae projecting from the
surface of many eukaryotic cells. They play important roles in mechano-and chemosensory …