Trans-species polymorphism in humans and the great apes is generally maintained by balancing selection that modulates the host immune response
Known examples of ancient identical-by-descent genetic variants being shared between
evolutionarily related species, known as trans-species polymorphisms (TSPs), result from …
evolutionarily related species, known as trans-species polymorphisms (TSPs), result from …
MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer
Tasmanian devils face extinction owing to the emergence of a contagious cancer. Devil
facial tumour disease (DFTD) is a clonal cancer spread owing to a lack of major …
facial tumour disease (DFTD) is a clonal cancer spread owing to a lack of major …
Marsupial immunology bounding ahead
Marsupial immune responses were previously touted as 'primitive'but we now know that the
marsupial immune system is complex and on par with that of eutherian mammals. In this …
marsupial immune system is complex and on par with that of eutherian mammals. In this …
Low MHC class II diversity in the Tasmanian devil (Sarcophilus harrisii)
The largest remaining carnivorous marsupial, the Tasmanian devil (Sarcophilus harrisii), is
currently under threat of extinction due to a fatal contagious cancer—devil facial tumour …
currently under threat of extinction due to a fatal contagious cancer—devil facial tumour …
Immigration rates in fragmented landscapes–empirical evidence for the importance of habitat amount for species persistence
T Puettker, AA Bueno, C dos Santos de Barros… - PloS one, 2011 - journals.plos.org
Background The total amount of native vegetation is an important property of fragmented
landscapes and is known to exert a strong influence on population and metapopulation …
landscapes and is known to exert a strong influence on population and metapopulation …
Trans-species polymorphism of the Mhc class II DRB-like gene in banded penguins (genus Spheniscus)
EF Kikkawa, TT Tsuda, D Sumiyama, TK Naruse… - Immunogenetics, 2009 - Springer
Abstract The Major Histocompatibility Complex (Mhc) class II DRB locus of vertebrates is
highly polymorphic and some alleles may be shared between closely related species as a …
highly polymorphic and some alleles may be shared between closely related species as a …
Contrasting evolutionary histories of MHC class I and class II loci in grouse—effects of selection and gene conversion
Genes of the major histocompatibility complex (MHC) encode receptor molecules that are
responsible for recognition of intracellular and extracellular pathogens (class I and class II …
responsible for recognition of intracellular and extracellular pathogens (class I and class II …
The tammar wallaby major histocompatibility complex shows evidence of past genomic instability
Background The major histocompatibility complex (MHC) is a group of genes with a variety
of roles in the innate and adaptive immune responses. MHC genes form a genetically linked …
of roles in the innate and adaptive immune responses. MHC genes form a genetically linked …
Drift Rather than Selection Dominates MHC Class II Allelic Diversity Patterns at the Biogeographical Range Scale in Natterjack Toads Bufo calamita
I Zeisset, TJC Beebee - PLoS One, 2014 - journals.plos.org
Study of major histocompatibility complex (MHC) loci has gained great popularity in recent
years, partly due to their function in protecting vertebrates from infections. This is of particular …
years, partly due to their function in protecting vertebrates from infections. This is of particular …
Reduced MHC class II diversity in island compared to mainland populations of the black-footed rock-wallaby (Petrogale lateralis lateralis)
RAB Mason, TL Browning, MDB Eldridge - Conservation Genetics, 2011 - Springer
Many animal populations that are endangered in mainland areas exist in stable island
populations, which have the potential to act as an “ark” in case of mainland population …
populations, which have the potential to act as an “ark” in case of mainland population …