Endosome dysregulation in down syndrome: a potential contributor to Alzheimer disease pathology
A Filippone, D Praticò - Annals of neurology, 2021 - Wiley Online Library
Intracellular protein trafficking via the endosomes plays a key role in the maintenance of
normal neuronal function. Although many diseases of the central nervous system exhibit …
normal neuronal function. Although many diseases of the central nervous system exhibit …
[HTML][HTML] Role of the cystathionine β-synthase/H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome
Background Overexpression of the transsulfuration enzyme cystathionine-β-synthase (CBS),
and overproduction of its product, hydrogen sulfide (H 2 S) are recognized as potential …
and overproduction of its product, hydrogen sulfide (H 2 S) are recognized as potential …