The origin and evolution of lignin biosynthesis

JK Weng, C Chapple - New Phytologist, 2010 - Wiley Online Library
Lignin, a phenolic polymer derived mainly from hydroxycinnamyl alcohols, is ubiquitously
present in tracheophytes. The development of lignin biosynthesis has been considered to be …

Voltage-gated proton channels and other proton transfer pathways

TE Decoursey - Physiological reviews, 2003 - journals.physiology.org
Proton channels exist in a wide variety of membrane proteins where they transport protons
rapidly and efficiently. Usually the proton pathway is formed mainly by water molecules …

Mitochondrial uncouplers induce proton leak by activating AAC and UCP1

AM Bertholet, AM Natale, P Bisignano, J Suzuki… - Nature, 2022 - nature.com
Mitochondria generate heat due to H+ leak (IH) across their inner membrane. IH results from
the action of long-chain fatty acids on uncoupling protein 1 (UCP1) in brown fat,,,–and …

Mitochondrial H+ Leak and Thermogenesis

AM Bertholet, Y Kirichok - Annual review of physiology, 2022 - annualreviews.org
Mitochondria of all tissues convert various metabolic substrates into two forms of energy:
ATP and heat. Historically, the primary focus of research in mitochondrial bioenergetics was …

Uncouplers of oxidative phosphorylation.

H Terada - Environmental health perspectives, 1990 - ehp.niehs.nih.gov
Uncouplers of oxidative phosphorylation in mitochondria inhibit the coupling between the
electron transport and phosphorylation reactions and thus inhibit ATP synthesis without …

Barrier function of epithelia

DW Powell - American Journal of Physiology …, 1981 - journals.physiology.org
The ability of an epithelium to prevent permeation of noxious agents has not been well
studied except in the gastrointestinal tract where exclusion of H+ has clinical significance …

Mitochondrial targets of drug toxicity

KB Wallace, AA Starkov - Annual review of pharmacology and …, 2000 - annualreviews.org
Mitochondria have long been recognized as the generators of energy for the cell. Like any
other power source, however, mitochondria are highly vulnerable to inhibition or uncoupling …

Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis

W Li, A Upadhyay, FL Fontes, EJ North… - Antimicrobial agents …, 2014 - Am Soc Microbiol
ABSTRACT MmpL3, a resistance-nodulation-division (RND) superfamily transporter, has
been implicated in the formation of the outer membrane of Mycobacterium tuberculosis; …

Effect of fatty acids on energy coupling processes in mitochondria

L Wojtczak, P Schönfeld - Biochimica et Biophysica Acta (BBA) …, 1993 - Elsevier
Effect of fatty acids on energy coupling processes in mitochondria - ScienceDirect Skip to
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Exploiting the Catenane Mechanical Bond Effect for Selective Halide Anion Transmembrane Transport

H Min Tay, TG Johnson, A Docker… - Angewandte Chemie …, 2023 - Wiley Online Library
The first examples of [2] catenanes capable of selective anion transport across a lipid bilayer
are reported. The neutral halogen bonding (XB)[2] catenanes were prepared via a chloride …