Introduction: High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that
promotes inflammation when released extracellularly after cellular activation, stress …

High-mobility group box 1 (HMGB1) is one of the most abundant proteins in eukaryotes and
the best characterized damage-associated molecular pattern (DAMP). The biological …

Although much has been made of the role of HMGB1 acting as an acute damage associated
molecular pattern (DAMP) molecule, prompting the response to tissue damage or injury, it is …

Systemic lupus erythematosus (SLE) is a complex and highly heterogeneous disease, which
affects multiple organs, including joints, skin, kidneys, heart, hematopoietic system, and …

Macrophage activation syndrome (MAS) is hyperinflammatory life-threatening syndrome,
associated typically with high levels of serum ferritin. This is an iron storage protein including …

Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease characterized
by arterial and/or venous thrombosis, pregnancy morbidity in the presence of circulating …

Abstract Background The Renal Activity Index for Lupus (RAIL) consists of urine protein
assessment of neutrophil gelatinase–associated lipocalin, kidney injury molecule-1 …

Rheumatic diseases, a group of diseases whose etiology is still unclear, are thought to be
related to genetic and environmental factors, leading to complex pathogenesis. Based on …

Purpose Accumulative studies showed that tumor necrosis factor (TNF)-like weak inducer of
apoptosis (TWEAK) was up-regulated in the blood and urine from patients diagnosed with …

目的探讨血清高迁移率族蛋白B1 (HMGB1), 胰岛素样生长因子1 (IGF⁃ 1) 和血管内皮生长因子
165 (VEGF165) 水平与糖尿病肾病(DN) 病情进展的相关性. 方法选择2016 年1 月至2018 年1 …